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Feet of a baby born to a mother who had taken thalidomide while pregnant. In the late 1950s and early 1960s, the use of thalidomide in 46 countries was prescribed to women who were pregnant or who subsequently became pregnant, and consequently resulted in the "biggest anthropogenic medical disaster ever," with more than 10,000 children born with a range of severe deformities, such as ...
Wonder Drug: The Secret History of Thalidomide in America and Its Hidden Victims is a nonfiction book authored by Jennifer Vanderbes and published by Random House in 2023. It tells the story of how Frances Oldham Kelsey of the Food and Drug Administration (FDA) found flaws in thalidomide research.
Thalidomide is racemic; while S-thalidomide is the bioactive form of the molecule, the individual enantiomers can racemize to each other due to the acidic hydrogen at the chiral centre, which is the carbon of the glutarimide ring bonded to the phthalimide substituent. The racemization process can occur in vivo.
Cuba’s crisis is the result of the internal blockade enforced by the Cuban government on the Cuban people. Cuban American scholar Dr. Amalia Daché has said that “…lifting the embargo would ...
Photo Illustration by Thomas Levinson/The Daily Beast/GettyThe UN General Assembly just voted for the 30th consecutive year to condemn America’s economic embargo on Cuba. Yes, you read that ...
Cuba attempted to embargo the U.S. by banning U.S. cash deposits at Cuban banks in 2021 but had to reverse the ban due to economic distress in 2023. [73] The U.S. government eased select financial sanctions against companies that serve Cuban interests but have no link to the Cuban government in 2024. [ 74 ]
Thalidomide: 1961 Germany Withdrawn because of risk of teratogenicity; [62] returned to market for use in leprosy and multiple myeloma under FDA orphan drug rules Thenalidine: 1963 Canada, UK, US Neutropenia [3] [63] Thiobutabarbitone: 1993 Germany Kidney injury. [3] Thioridazine (Melleril) 2005 Germany, UK
Concerns have been expressed about the operation of due process.According to Human Rights Watch, even though Cuba, officially atheist until 1992, now "permits greater opportunities for religious expression than it did in past years, and has allowed several religious-run humanitarian groups to operate, the government still maintains tight control on religious institutions, affiliated groups ...