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Download the PDF. This one-page snapshot provides a high-level summary of the guidelines on the types of interventions that should be used to prevent VTE in hospitalized and non-hospitalized medical patients. A snapshot of the full VTE guidelines is also available for download.
This document serves as a clinical guideline for primary prevention of venous thromboembolism (VTE) in adult patients hospitalized for ≥ 24 hours or who may qualify for primary VTE prophylaxis upon discharge.
The American Society of Hematology (ASH) has long recognized the need for a comprehensive set of guidelines for hematologists and other clinicians on venous thromboembolism (VTE), a common and serious blood clotting condition that includes both deep-vein thrombosis (DVT) and pulmonary embolism (PE).
In patients with acute VTE in the setting of cancer (cancer-associated thrombosis) we recommend an oral Xa inhibitor (apixaban, edoxaban, rivaroxaban) over low molecular weight heparin (LMWH) for the initiation and treatment phases of therapy (strong recommendation, moderate-certainty evidence).
Pharmacologic prophylactic and treatment options for VTE consist of UFH, LMWHs, fondaparinux (an indirect synthetic inhibitor of activated factor Xa), VKAs, and DOACs, including direct thrombin inhibitors (dabigatran) and direct factor Xa inhibitors (apixaban, edoxaban, and rivaroxaban). 30,39 Consideration for the prophylaxis or treatment of ...
Update information. August 2021: This quality standard updates and replaces the quality standards on venous thromboembolism in adults: reducing the risk in hospital (published June 2010), and venous thromboembolism in adults: diagnosis and management (published March 2013).
VTE prophylaxis will be initiated within 72 hrs of the injury/procedure for most intra-cranial hemorrhages and after craniotomy. Prophylaxis may be considered 24 hrs after admission for patients with mild TBI and the following: GCS of 15 within 30 minutes of injury.
Strong recommendations include not using thromboprophylaxis in ambulatory patients receiving cancer chemotherapy at low risk of VTE and to use low-molecular-weight heparin (LMWH) for initial treatment of VTE in patients with cancer.
recommendations, covering aspects of antithrombotic management of VTE from initial management through secondary prevention and risk reduction of postthrombotic syn- drome.
The American Society of Hematology has updated recommendations for management of VTE, which includes deep venous thrombosis (DVT) and pulmonary embolism (PE).