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  2. Coefficient of inbreeding - Wikipedia

    en.wikipedia.org/wiki/Coefficient_of_inbreeding

    The coefficient of inbreeding (COI) is a number measuring how inbred an individual is. Specifically, it is the probability that two alleles at any locus in an individual are identical by descent from a common ancestor of the two parents. [1][2][3][4] A higher COI will make the traits of the offspring more predictable, but also increases the ...

  3. Positive feedback - Wikipedia

    en.wikipedia.org/wiki/Positive_feedback

    [1] [3] Both concepts play an important role in science and engineering, including biology, chemistry, and cybernetics. Mathematically, positive feedback is defined as a positive loop gain around a closed loop of cause and effect. [1] [3] That is, positive feedback is in phase with the input, in the sense that it adds to make the input larger.

  4. Self-replication - Wikipedia

    en.wikipedia.org/wiki/Self-replication

    Self-replication is a fundamental feature of life. It was proposed that self-replication emerged in the evolution of life when a molecule similar to a double-stranded polynucleotide (possibly like RNA) dissociated into single-stranded polynucleotides and each of these acted as a template for synthesis of a complementary strand producing two double stranded copies. [4]

  5. Stem-loop - Wikipedia

    en.wikipedia.org/wiki/Stem-loop

    Stem-loop. Stem-loops are nucleic acid secondary structural elements which form via intramolecular base pairing in single-stranded DNA or RNA. They are also referred to as hairpins or hairpin loops. A stem-loop occurs when two regions of the same nucleic acid strand, usually complementary in nucleotide sequence, base-pair to form a double helix ...

  6. Topologically associating domain - Wikipedia

    en.wikipedia.org/wiki/Topologically_associating...

    A topologically associating domain (TAD) is a self-interacting genomic region, meaning that DNA sequences within a TAD physically interact with each other more frequently than with sequences outside the TAD. [ 1 ] The average size of a topologically associating domain (TAD) is 1000 kb in humans, 880 kb in mouse cells, and 140 kb in fruit flies ...

  7. Mathematical and theoretical biology - Wikipedia

    en.wikipedia.org/wiki/Mathematical_and...

    Theoretical biology focuses more on the development of theoretical principles for biology while mathematical biology focuses on the use of mathematical tools to study biological systems, even though the two terms are sometimes interchanged. [ 3 ][ 4 ] Mathematical biology aims at the mathematical representation and modeling of biological ...

  8. Bioinformatics - Wikipedia

    en.wikipedia.org/wiki/Bioinformatics

    Bioinformatics uses biology, chemistry, physics, computer science, computer programming, information engineering, mathematics and statistics to analyze and interpret biological data. The subsequent process of analyzing and interpreting data is often referred to as computational biology, though the distinction between the two terms is often ...

  9. Feedback - Wikipedia

    en.wikipedia.org/wiki/Feedback

    The climate system is characterized by strong positive and negative feedback loops between processes that affect the state of the atmosphere, ocean, and land. A simple example is the ice–albedo positive feedback loop whereby melting snow exposes more dark ground (of lower albedo), which in turn absorbs heat and causes more snow to melt.