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  2. Glomerular filtration rate - Wikipedia

    en.wikipedia.org/wiki/Glomerular_filtration_rate

    The normal range of GFR, adjusted for body surface area, is 100–130 average 125 mL/min/1.73m 2 in men and 90–120 ml/min/1.73m 2 in women younger than the age of 40. In children, GFR measured by inulin clearance is 110 mL/min/1.73 m 2 until 2 years of age in both sexes, and then it progressively decreases. After age 40, GFR decreases ...

  3. Assessment of kidney function - Wikipedia

    en.wikipedia.org/wiki/Assessment_of_kidney_function

    The severity of chronic kidney disease (CKD) is described by six stages; the most severe three are defined by the MDRD-eGFR value, and first three also depend on whether there is other evidence of kidney disease (e.g., proteinuria): 0) Normal kidney function – GFR above 90 (mL/min)/(1.73 m 2) and no proteinuria

  4. Creatinine - Wikipedia

    en.wikipedia.org/wiki/Creatinine

    Algorithms to estimate GFR from creatinine concentration and other parameters are discussed in the renal function article. Unfortunately, the MDRD Study equation was developed in people with chronic kidney disease, and its major limitations are imprecision and systematic underestimation of measured GFR (bias) at higher/normal values. [20]

  5. Basic metabolic panel - Wikipedia

    en.wikipedia.org/wiki/Basic_metabolic_panel

    Outside the United States, blood tests made up of the majority of the same biochemical tests are called urea and electrolytes (U&E or "U and Es"), or urea, electrolytes, creatinine (UEC or EUC or CUE), and are often referred to as 'kidney function tests' as they also include a calculated estimated glomerular filtration rate. The BMP provides ...

  6. Filtration fraction - Wikipedia

    en.wikipedia.org/wiki/Filtration_fraction

    GFR on its own is the most common and important measure of renal function. However, in conditions such as renal artery stenosis, blood flow to the kidneys is reduced. Filtration fraction must therefore be increased in order to perform the normal functions of the kidney. Loop diuretics and thiazide diuretics decrease filtration fraction.

  7. Diabetic nephropathy - Wikipedia

    en.wikipedia.org/wiki/Diabetic_nephropathy

    To clinically stage the degree of damage in this (and any) kidney disease, the serum creatinine is determined and used to calculate the estimated glomerular filtration rate . Normal eGFR is equal to or greater than 90ml/min/1.73 m 2. [34] On biopsy, the following classification has been suggested by Tervaert et al.: [35]

  8. EGFR - Wikipedia

    en.wikipedia.org/wiki/EGFR

    EGFR may refer to: Epidermal growth factor receptor (EGFR), a transmembrane receptor protein in humans Estimated glomerular filtration rate (eGFR), a measure of renal function

  9. Glomerular hyperfiltration - Wikipedia

    en.wikipedia.org/wiki/Glomerular_hyperfiltration

    The primary cause of the lack of clarity surrounding the GFR levels that indicate hyperfiltration is their strong reliance on age. [12] Glomerular hyperfiltration has traditionally been characterized as an elevated whole-kidney GFR, or a GFR greater than two standard deviations above the mean GFR of healthy individuals.

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