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Life-cycle of a typical virus (left to right); following infection of a cell by a single virus, hundreds of offspring are released. When a virus infects a cell, the virus forces it to make thousands more viruses. It does this by making the cell copy the virus's DNA or RNA, making viral proteins, which all assemble to form new virus particles. [37]
The capsid and entire virus structure can be mechanically (physically) probed through atomic force microscopy. [43] [44] In general, there are five main morphological virus types: Helical These viruses are composed of a single type of capsomere stacked around a central axis to form a helical structure, which may have a central cavity, or tube ...
Structure of a virus, specifically the hepatitis C virus. Viruses, infectious agents composed of a protein coat that encloses a genome, are the most numerous biological entities on Earth. [1] [2] As they cannot replicate independently, they must infect cells and hijack the host's replication machinery in order to produce copies of themselves. [2]
Virus factors encoded in the genome often control the tropism, routes of virus entry, shedding and transmission. In polioviruses, the attenuating point mutations are thought to induce a replication and translation defect to reduce the virus' ability of cross-linking to host cells and replicate within the nervous system.
Often simply called an antiviral. A class of antimicrobial medication used specifically for treating diseases caused by viral infections rather than ones caused by bacteria or other infectious agents. Unlike most antibiotics, antivirals typically do not destroy their target viruses but instead inhibit their development. They are distinct from virucides. assembly The construction of the virus ...
To enter the cells, proteins on the surface of the virus interact with proteins of the cell. Attachment, or adsorption, occurs between the viral particle and the host cell membrane. A hole forms in the cell membrane, then the virus particle or its genetic contents are released into the host cell, where replication of the viral genome may commence.
Entry, or penetration, is the second step in viral replication. This step is characterized by the virus passing through the plasma membrane of the host cell. The most common way a virus gains entry to the host cell is by receptor-mediated endocytosis, which comes at no energy cost to the virus, only the host cell. Receptor-mediated endocytosis ...
A viral disease (or viral infection) occurs when an organism's body is invaded by pathogenic viruses, and infectious virus particles (virions) attach to and enter susceptible cells. [ 1 ] Examples include the common cold , gastroenteritis , COVID-19 , the flu , and rabies .