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  2. Vardenafil - Wikipedia

    en.wikipedia.org/wiki/Vardenafil

    Vardenafil's indications and contraindications are the same as with other PDE5 inhibitors; it is closely related in function to sildenafil citrate (Viagra) and tadalafil (Cialis). The difference between the vardenafil molecule and sildenafil citrate is a nitrogen atom's position and the change of sildenafil's piperazine ring methyl group to an ...

  3. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

    www.aol.com/ed-pill-guide-everything-know...

    Whether you’re one of the 30 million men who have (ED) or not, you’ve almost certainly heard of Viagra. Maybe you even know about other ED medications, like Levitra or Stendra or Cialis, too.

  4. 4 Common ED Pills: Weighing the Pros & Cons of Each - AOL

    www.aol.com/4-common-ed-pills-weighing-141800609...

    The Best ED Medication for Men: Pros & Cons of Top ED Pills. Over the last 25 years, (ED) medications like Viagra and Cialis have become common fixtures in bedrooms around the world.

  5. Things You Probably Don't Know About Viagra (Like What It Was ...

    www.aol.com/things-probably-dont-know-viagra...

    Whether you’re a senior in high school or a senior-living resident, you’ve likely heard of Viagra (sildenafil) — the original medication for ED. Most men and women know at least vaguely what ...

  6. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

  7. Erectile dysfunction - Wikipedia

    en.wikipedia.org/wiki/Erectile_dysfunction

    Erectile dysfunction (ED), also referred to as impotence, is a form of sexual dysfunction in males characterized by the persistent or recurring inability to achieve or maintain a penile erection with sufficient rigidity and duration for satisfactory sexual activity.

  8. What Is the Safest ED Medication? - AOL

    www.aol.com/safest-ed-medication-105700669.html

    For example, headache — the most common side effect of most oral ED medication — was reported by 21 percent of men who used sildenafil citrate in clinical trials at a 50mg dosage.

  9. Sildenafil - Wikipedia

    en.wikipedia.org/wiki/Sildenafil

    Sildenafil is excreted as metabolites predominantly in the feces (about 80% of administered oral dose) and to a lesser extent in the urine (around 13% of the administered oral dose). If taken with a high-fat meal, absorption is reduced; the time taken to reach the maximum plasma concentration increases by around one hour, and the maximum ...

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