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Trichomonas vaginalis May-Grünwald-Giemsa staining. The spike-like axostyle can be seen on the left. Trichomonas vaginalis exists in only one morphological stage, a trophozoite, and cannot encyst (or form cysts.) This protozoan does not typically adhere to one shape, as in different conditions, the parasite has the ability to change.
Trichomoniasis (trich) is an infectious disease caused by the parasite Trichomonas vaginalis. [2] About 70% of affected people do not have symptoms when infected. [2] When symptoms occur, they typically begin 5 to 28 days after exposure. [1]
Trichomonas vaginalis, being the species that causes the most complications in humans, is the only fully sequenced Trichomonas species. Through whole-genome shotgun sequencing, the Trichomonas vaginalis genome is estimated to be around 160 Mb long, divided into six chromosomes. However, at least 65% of its genome was found to be redundant.
Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment to host receptors, which mediates endocytosis. Replication follows the double-stranded RNA virus replication model. Double-stranded RNA virus transcription is the method of transcription. Protozoan parasite trichomonas vaginalis serve as the natural host. [1]
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The trichomonads have one group of 4–6 flagella, one of which is attached to the side of the cell and often forms an undulating membrane. Many are found in vertebrate hosts, including Trichomonas vaginalis, which causes a sexually transmitted disease in humans.
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