Search results
Results from the WOW.Com Content Network
Titin [2] (/ ˈ t aɪ t ɪ n /; also called connectin) is a protein that in humans is encoded by the TTN gene. [3] [4] The protein, which is over 1 μm in length, [5] functions as a molecular spring that is responsible for the passive elasticity of muscle. It comprises 244 individually folded protein domains connected by unstructured peptide ...
In nature, DNA molecules can be much bigger than protein molecules and therefore potentially be referred to with much longer chemical names. For example, the wheat chromosome 3B contains almost 1 billion base pairs, [19] so the sequence of one of its strands, if written out in full like Adenilyladenilylguanilylcystidyl thymidyl . . .
Thick filaments consist primarily of the protein myosin, that is responsible for force generation. It is composed of a globular head with both ATP and actin binding sites, and a long tail involved in its polymerization into myosin filaments. Elastic filaments are made up of a giant protein called titin and hold the thick filaments in place.
58916 Ensembl ENSG00000120729 ENSMUSG00000024471 UniProt Q9UBF9 Q9JIF9 RefSeq (mRNA) NM_006790 NM_001135940 NM_001300911 NM_001033621 RefSeq (protein) NP_001129412 NP_001287840 NP_006781 NP_001028793 Location (UCSC) Chr 5: 137.87 – 137.89 Mb Chr 18: 44.47 – 44.49 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Myotilin is a protein that in humans is encoded by the MYOT gene ...
The main proteins involved are myosin, actin, and titin. Myosin and actin are the contractile proteins and titin is an elastic protein. The myofilaments act together in muscle contraction, and in order of size are a thick one of mostly myosin, a thin one of mostly actin, and a very thin one of mostly titin. [1] [2]
Obscurin has been shown to interact with Titin, [5] [31] specifically, with the Novex-3 of Titin, a 6.5 kb exon located upstream of the cardiac-specific N2B exon. [32] The C-terminal region of Obscurin interacts with the cytoplasmic domain of small ankyrin 1 [33] [34] and with the exon 43' region of ankyrin B. [35]
21393 Ensembl ENSG00000173991 ENSMUSG00000007877 UniProt O15273 O70548 RefSeq (mRNA) NM_003673 NM_011540 RefSeq (protein) NP_003664 NP_003664.1 NP_035670 Location (UCSC) Chr 17: 39.67 – 39.67 Mb Chr 11: 98.27 – 98.28 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Telethonin, also known as Tcap, is a protein that in humans is encoded by the TCAP gene. Telethonin is expressed in ...
Myomesin is bound to myosin at its N-terminal. Obscurin connects the myomesin dimers and binds to the C-terminal of titin. It is thought that the myomesin-titin interaction is vital for the execution of the mechanical functions of the Ser/Thr kinase domain of titin. [2] Myomesin is a protein family found in the M-line of the sarcomere structure.