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Poorly controlled asthma is a common finding, with a case series only finding 19% of ABPA patients with well-controlled asthma. Wheezing and hemoptysis (coughing up blood) are common features, and mucus plugging is seen in 31–69% of patients. [11]
Occupational asthma – an estimated 2% to 5% of all asthma episodes may be caused by exposure to a specific sensitizing agent in the workplace. Nocturnal asthma is a characteristic problem in poorly controlled asthma and is reported by more than two-thirds of sub-optimally treated patients.
Poorly controlled aspergillosis can disseminate through the blood to cause widespread organ damage. [2] Symptoms include fever, chills, shock, delirium, seizures, and blood clots. The person may develop kidney failure, liver failure (causing jaundice), and breathing difficulties. [2] Death can occur quickly.
While the potential triggering events for EIB are well recognized, the underlying pathogenesis is poorly understood. [4] It usually occurs after at least several minutes of vigorous, aerobic activity, which increases oxygen demand to the point where breathing through the nose ( nasal breathing ) must be supplemented by mouth breathing .
Asthma, particularly severe asthma, is strongly associated with development of chronic obstructive pulmonary disease (COPD). [31] [32] [33] Those with asthma, especially if it is poorly controlled, are at increased risk for radiocontrast reactions. [34] Cavities occur more often in people with asthma. [35]
If the person with a severe asthma exacerbation is on a mechanical ventilator, certain sedating medications such as ketamine or propofol, have bronchodilating properties. According to a new randomized control trial ketamine and aminophylline are also effective in children with acute asthma who responds poorly to standard therapy. [9]
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With emphysema the shortness of breath due to effective bronchoconstriction from excessive very thick mucus blockage (it is so thick that great difficulty is encountered in expelling it resulting in near exhaustion at times) can bring on panic attacks unless the individual expects this and has effectively learned pursed lip breathing to more quickly transfer oxygen to the blood via the damaged ...