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Ichthammol or ammonium bituminosulfonate (brand name Ichthyol), also known as black ointment, is a medication derived from sulfur-rich oil shale (bituminous schists). It is used (sometimes in combination with zinc oxide ) as a treatment for different skin diseases , including eczema and psoriasis (see below).
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Proteases such as trypsin and clostridiopeptidase, which are contained in ointments used for the removal of dead skin on wounds, can be inhibited by silver ions if applied simultaneously. When silver sulfadiazine is absorbed in significant amounts, it can increase effects and side effects of some drugs such as vitamin K antagonists. [11]
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Side effects may include irritation of the skin and discoloration of clothing. [2] A harsh burn on a child from an undissolved tablet has been reported. [10] For treating eczema, it is recommended using for a few days at a time due to the possibility of it irritating the skin. [10] Higher concentration solutions can result in chemical burns. [11]
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