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Peptic ulcer disease is a break in the inner lining of the stomach, the first part of the small intestine, or sometimes the lower esophagus. [1] [7] An ulcer in the stomach is called a gastric ulcer, while one in the first part of the intestines is a duodenal ulcer. [1]
Zollinger-Ellison syndrome (ZES) is caused by a gastrinoma, which is a gastrin-producing tumor that causes gastric acid hypersecretion. [11] The main clinical manifestations of ZES are peptic ulcers and diarrhea. [12] The initial diagnostic test for ZES is a fasting serum gastrin level when antisecretory medications are stopped. If the gastrin ...
The primary goal of the treatment is not only temporary relief of symptoms but also total elimination of H. pylori infection. Patients with active duodenal or gastric ulcers and those with a prior ulcer history should be tested for H. pylori. Appropriate therapy should be given for eradication.
For example, in about 10% of the American public, gastric or peptic ulcers can become a problem. Ulcers are sores that form in soft tissue, such as the lining of the digestive tract, and gastric ...
The H 2 receptor antagonists are a class of drugs used to block the action of histamine on parietal cells in the stomach, decreasing the production of acid by these cells. H 2 antagonists are used in the treatment of dyspepsia, although they have been surpassed in popularity by the more effective [1] proton pump inhibitors.
Chlordiazepoxide/clidinium bromide (marketed as Librax) is a fixed-dose combination medication used to treat peptic ulcers, irritable bowel syndrome (IBS), and gastritis. [2] It contains chlordiazepoxide and clidinium bromide. It helps relieve stomach spasms, abdominal cramps, and anxiety related to gastric disorders. [3]
Sucralfate is used for the treatment of active duodenal ulcers not related to the use of nonsteroidal anti-inflammatory drugs (NSAIDs), as the mechanism behind these ulcers is due to acid oversecretion. [1] It is not FDA approved for gastric ulcers, but is widely used because of evidence of efficacy. [10]
An anti-ulcer medication for treating mouth ulcer is triamcinolone, a corticosteroid. Other anti-ulcer supplements include vitamin B2 and vitamin B12 . Antibiotics and agents to reduce gastric acid secretion are used in combinations to treat Helicobacter pylori ( H. pylori )-induced peptic ulcer disease (PUD), an ulceration in the gastric region.