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Rivaroxaban, sold under the brand name Xarelto among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. [8] Specifically it is used to treat deep vein thrombosis and pulmonary emboli and prevent blood clots in atrial fibrillation and following hip or knee surgery. [ 8 ]
Antistasin, the first discovered naturally occurring direct Xa inhibitor Rivaroxaban, the first synthetic direct Xa inhibitor marketed as a drug Prior to the introduction of direct factor Xa inhibitors, vitamin K antagonists such as warfarin were the only oral anticoagulants for over 60 years, and together with heparin have been the main blood ...
Rivaroxaban. During the SAR development of rivaroxaban, researchers realized that adding a 5-chlorothiophene-2-carboxamide group to the oxazolidonine core could increase the potency by 200 fold, which had previously been too weak for medical use. In addition to this discovery, a clear preference for the (S)-configuration was confirmed.
Skeletal formulae of the antibiotic linezolid (top) and the anticoagulant rivaroxaban (bottom), highlighting their similar oxazolidinone core (in blue). Created using ACD/ChemSketch 10.0 and Inkscape. Date: 11 June 2009: Source: Own work. The structural similarity between the drugs is discussed in European Medicines Agency (2008).
If you suffer from eczema and your sensitive skin is prone to flare-ups, dermatologists suggest these gentle body washes—all suitable for the skin condition. Dermatologists Say This Body Wash ...
Here, the benefits of a body wash for dry skin and formulas that will transform your shower and skin. Discover affordable drugstore options to luxury picks.
An anticoagulant, commonly known as a blood thinner, is a chemical substance that prevents or reduces the coagulation of blood, prolonging the clotting time. [1] Some occur naturally in blood-eating animals, such as leeches and mosquitoes, which help keep the bite area unclotted long enough for the animal to obtain blood.
The following other wikis use this file: Usage on ar.wikipedia.org ريفاروكسابان; Usage on azb.wikipedia.org ریواروکسابان