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The odor detection threshold for phosgene is 0.4 ppm, four times the threshold limit value (time weighted average). Its high toxicity arises from the action of the phosgene on the −OH , −NH 2 and −SH groups of the proteins in pulmonary alveoli (the site of gas exchange), respectively forming ester, amide and thioester functional groups in ...
The threshold dose-response model is widely viewed as the most dominant model in toxicology. [6] An alternative type of model in toxicology is the linear no-threshold model (LNT), while hormesis correspond to the existence of opposite effects at low vs. high dose, which usually gives a U- or inverted U-shaped dose response curve.
A box model explaining the processes of toxicokinetics and toxicodynamics. While toxicokinetics describes the changes in the concentrations of a toxicant over time due to the uptake, biotransformation, distribution and elimination of toxicants, toxicodynamics involves the interactions of a toxicant with a biological target and the functional or structural alterations in a cell that can ...
The value of threshold smell greatly depends on how much attention people pay to it, and on their health status. The sensitivity may be reduced, for example, due to colds and other ailments. It turns out that a worker's ability to detect smell also depends on the nature of the work to be performed — if it requires concentration, a user may ...
3D model . Interactive image; ChEMBL: ... Freon 113, like most chlorofluoroalkanes, forms phosgene gas when exposed to a naked flame. [19] See also
Traces of a toxic, colorless gas were found at the headquarters of Sweden’s security agency where a suspected gas leak last week forced authorities to evacuate some 500 people from the facility ...
Phosgene oxime, or CX, is an organic compound with the formula Cl 2 C=N−O H. It is a potent chemical weapon , specifically a nettle agent . The compound itself is a colorless solid, but impure samples are often yellowish liquids.
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