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Sodium nitroprusside (SNP), sold under the brand name Nitropress among others, is a medication used to lower blood pressure. [3] This may be done if the blood pressure is very high and resulting in symptoms , in certain types of heart failure , and during surgery to decrease bleeding . [ 3 ]
Nitrates undergo chemical reduction, likely mediated by enzymes. Molsidomine and nitroprusside already contain nitrogen in the right oxidation state (+2) and liberate NO without the aid of enzymes. [3] NO stimulates the soluble form of the enzyme guanylate cyclase in the smooth muscle cells of blood vessels.
Date/Time Thumbnail Dimensions User Comment; current: 10:30, 17 June 2010: 600 × 480 (25 KB): Divide: Spectrum can be seen more clearly (bigger markers). 10:27, 17 June 2010
Atherosclerosis is characterized by the build-up of plaque inside your blood vessels. It can lead to stenosis, which is a narrowing of your artery walls. Plaque is a fatty substance made up of:
Vasodilation plays a major role in immune system function. Wider blood vessels allow more blood containing immune cells and proteins to reach the infection site. Vasodilation occurs as part of the process of inflammation, which is caused by several factors including presence of a pathogen, injury to tissues or blood vessels, and immune ...
Sodium nitroprusside, a medicinally significant metal nitrosyl-pentacyanoferrate (Fe-III) compound, used to treat hypertension. [1] Metal nitrosyl complexes are complexes that contain nitric oxide, NO, bonded to a transition metal. [2] Many kinds of nitrosyl complexes are known, which vary both in structure and coligand.
Sodium nitroprusside is also contraindicated in patients with myocardial infarction, due to coronary steal. [9] It is again important that the blood pressure is lowered slowly. The initial goal in hypertensive emergencies is to reduce the pressure by no more than 25% the mean arterial pressure. Excessive reduction in blood pressure can ...
Nitric oxide synthases (NOSs) are a family of enzymes catalyzing the production of nitric oxide (NO) from L-arginine.NO is an important cellular signaling molecule. It helps modulate vascular tone, insulin secretion, airway tone, and peristalsis, and is involved in angiogenesis and neural development.