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Hemiplegic migraine is a type of migraine headache characterized by motor weakness affecting only one side of the body, accompanied by aura. There is often an impairment in vision, speech, or sensation. It can run in the family, called familial hemiplegic migraine, or in a single individual, called sporadic hemiplegic migraine.
Familial hemiplegic migraine (FHM) is an autosomal dominant type of hemiplegic migraine that typically includes weakness of half the body which can last for hours, days, or weeks. It can be accompanied by other symptoms, such as ataxia , coma , and paralysis.
Migraine: Migraine; Prevention of migraine attacks; Aura; Cortical spreading depression; ICHD classification and diagnosis of migraine. Retinal migraine; Familial hemiplegic migraine; Sporadic hemiplegic migraine
Sporadic hemiplegic migraine (SHM) has clinical symptoms identical to familial hemiplegic migraine (FHM) and distinct from migraine with aura. By definition the neurodeficits are supposed to be reversible. However, some cases with permanent neurological deficits have also been noted. [3]
Migraine with aura, or "classic migraine", usually involves migraine headaches accompanied by aura. Less commonly, aura can occur without a headache, or with a nonmigraine headache. Two other varieties are familial hemiplegic migraine and sporadic hemiplegic migraine, in which a person has migraine with aura and with accompanying motor weakness ...
Spelling's 14-year-old daughter is home and doing better after suffering stroke-like symptoms.
Single gene disorders that result in migraines are rare. [6] One of these is known as familial hemiplegic migraine, a type of migraine with aura, which is inherited in an autosomal dominant fashion. [7] [8] Four genes have been shown to be involved in familial hemiplegic migraine. [9] Three of these genes are involved in ion transport. [9]
One of the unique characteristics of AHC is that hemiplegic attacks, as well as other symptoms which may co-occur with hemiplegia, cease immediately upon sleep. During strong attacks, the symptoms may reoccur upon waking. [4] [6] Hemiplegic attacks can occur suddenly or gradually, and the severity of an attack can vary over its duration. [6]