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Although they are called untranslated regions, and do not form the protein-coding region of the gene, uORFs located within the 5' UTR can be translated into peptides. [1] The 5' UTR is upstream from the coding sequence. Within the 5' UTR is a sequence that is recognized by the ribosome which allows the ribosome to bind and initiate translation.
The Atlas of UTR Regulatory Activity (AURA), [1] a biological database, now at its second version, [2] is a manually curated and comprehensive catalog of human 5' and 3' untranslated sequences (UTR) and UTR regulatory annotations. It includes basic annotation, phylogenetic conservation, binding sites for RNA-binding proteins and miRNA, cis ...
The 5′ untranslated region (also known as 5′ UTR, leader sequence, transcript leader, or leader RNA) is the region of a messenger RNA (mRNA) that is directly upstream from the initiation codon. This region is important for the regulation of translation of a transcript by differing mechanisms in viruses , prokaryotes and eukaryotes .
In molecular genetics, the three prime untranslated region (3′-UTR) is the section of messenger RNA (mRNA) that immediately follows the translation termination codon. The 3′-UTR often contains regulatory regions that post-transcriptionally influence gene expression .
UTR can also be found on cable networks in Russia, Latvia, Kazakhstan and Turkey. Webcast on the official website is also available. The programming consists of Ukrainian produced films, news, cultural and educational programmes as well as programmes of some other Ukrainian channels. UTR broadcasts on VHF Channel 2 and replaced UT-2.
UTR may refer to: Ukrainian Television and Radio; Union of Translators of Russia; Unique Taxpayer Reference, a number HM Revenue and Customs assigns each UK taxpayer; Universal Tennis Rating, tennis player rating software; Untranslated region of mRNA, in genetics; UTR-Pickleball or UTR-P, pickleball player rating software
Adenylate-uridylate-rich elements (AU-rich elements; AREs) are found in the 3' untranslated region (UTR) of many messenger RNAs that code for proto-oncogenes, nuclear transcription factors, and cytokines. AREs are one of the most common determinants of RNA stability in mammalian cells. [1]