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An mRNA molecule is said to be monocistronic when it contains the genetic information to translate only a single protein chain (polypeptide). This is the case for most of the eukaryotic mRNAs. [28] [29] On the other hand, polycistronic mRNA carries several open reading frames (ORFs), each of which is translated into a polypeptide.
Shqip; Sicilianu ... (RNA) is a polymeric molecule that is essential for most biological functions, ... The mRNA is then exported from the nucleus to the cytoplasm, ...
An mRNA vaccine is a type of vaccine that uses a copy of a molecule called messenger RNA (mRNA) to produce an immune response. [1] The vaccine delivers molecules of antigen -encoding mRNA into cells , which use the designed mRNA as a blueprint to build foreign protein that would normally be produced by a pathogen (such as a virus ) or by a ...
Mature messenger RNA, often abbreviated as mature mRNA is a eukaryotic RNA transcript that has been spliced and processed and is ready for translation in the course of protein synthesis. Unlike the eukaryotic RNA immediately after transcription known as precursor messenger RNA , [ 1 ] mature mRNA consists exclusively of exons and has all ...
A normal mRNA starts and ends with sections that do not code for amino acids of the actual protein. These sequences at the 5′ and 3′ ends of an mRNA strand are called untranslated regions (UTRs). The two UTRs at their strand ends are essential for the stability of an mRNA and also of a modRNA as well as for the efficiency of translation, i ...
synonym for pre-mRNA (in the strict sense, it may include nuclear RNA transcripts that do not end up as cytoplasmic mRNA) RNAi: RNA interference - Process in which RNA inhibit gene expression or translation, by neutralizing targeted mRNA molecules lincRNA: long intergenic non-coding RNA - lncRNA: long non coding RNA - miRNA: micro RNA multiple ...
The 5′ end is the part of the RNA molecule that is transcribed first, and the 3′ end is transcribed last. The 3′ end is also where the poly(A) tail is found on polyadenylated RNAs. [1] [9] Messenger RNA (mRNA) is RNA that has a coding region that acts as a template for protein synthesis (translation).
The number of protein molecules synthesized using a given mRNA molecule as a template is highly dependent on translation-initiation features of the mRNA sequence; in particular, the ability of the translation initiation sequence is a key determinant in the recruiting of ribosomes for protein translation.