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A mucous membrane or mucosa is a membrane that lines various cavities in the body of an organism and covers the surface of internal organs. It consists of one or more layers of epithelial cells overlying a layer of loose connective tissue .
Cystitis glandularis at trigone. Cystitis glandularis is the transformation of mucosal cells lining the urinary bladder.They undergo glandular metaplasia, a process in which irritated tissues take on a different form, in this case that of a gland. [1]
As its Latin name indicates, it is a characteristic component of the mucosa, or the mucosa's "own special layer." Thus, the term mucosa or mucous membrane refers to the combination of the epithelium and the lamina propria. [1] The connective tissue of the lamina propria is loose and rich in cells.
In relation to interstitial cystitis, when noxious stimuli are present, it causes injury to the bladder mucosa resulting in recruitment of inflammatory cells. [3] Disruption of glycosaminoglycan (GAG) layer [ 14 ] along with the increased presence of mast cells , T cells , and B cells causes the bladder epithelium to become more permeable.
Transitional epithelial cells, also known as urothelial cells, line the urinary tract from the renal pelvis through the ureters and bladder and, in males, the upper portion of the urethra. They are smaller than squamous cells and their shape varies based on the layer of epithelium from which they are derived, but they are most commonly round or ...
In the gastrointestinal tract, the term mucosa or mucous membrane refers to the combination of epithelium, lamina propria, and (where it occurs) muscularis mucosae. [1] The etymology suggests this, since the Latin names translate to "the mucosa's own special layer" (lamina propria mucosae) and "muscular layer of the mucosa" (lamina muscularis ...
It forms an essential layer in the colon and in the small intestine that helps reduce intestinal inflammation by decreasing bacterial interaction with intestinal epithelial cells. [21] The layer of mucus of the gastric mucosa lining the stomach is vital to protect the stomach lining from the highly acidic environment within it. [22]
The female urethra is located between the bladder neck to the external urethral orifice and is behind the symphysis pubis. [4] The urethral wall is composed of an inner epithelial lining, a sub-mucosa layer containing vascular supply, a thin fascial layer, and two layers of smooth muscle. [4]