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When radiolabeled with 11 CH 3, choline is a useful a tracer in PET imaging. Carbon-11 is radioactive with a half-life of 20.38 minutes. [1] By monitoring the gamma radiation resulting from the decay of carbon-11, the uptake, distribution, and retention of carbon-11 choline can be monitored.
Positron emission tomography (PET) [1] is a functional imaging technique that uses radioactive substances known as radiotracers to visualize and measure changes in metabolic processes, and in other physiological activities including blood flow, regional chemical composition, and absorption.
Brain positron emission tomography is a form of positron emission tomography (PET) that is used to measure brain metabolism and the distribution of exogenous radiolabeled chemical agents throughout the brain. PET measures emissions from radioactively labeled metabolically active chemicals that have been injected into the bloodstream.
Another fraction of [18 F]FDG, representing about 20% of the total fluorine-18 activity of an injection, is excreted renally by two hours after a dose of [18 F]FDG, with a rapid half-life of about 16 minutes (this portion makes the renal-collecting system and bladder prominent in a normal PET scan). This short biological half-life indicates ...
Radiation poisoning, also called "radiation sickness" or a "creeping dose", is a form of damage to organ tissue due to excessive exposure to ionizing radiation. The term is generally used to refer to acute problems caused by a large dosage of radiation in a short period, though this also has occurred with long-term exposure to low-level radiation.
PET is a functional imaging technique that produces a three-dimensional image of functional processes in the body. The system detects pairs of gamma rays emitted indirectly by a positron -emitting radionuclide ( tracer ), which is introduced into the body on a biologically active molecule.
3-dimensional [18 F]FDG-PET image with 3D ROI generated by a threshold based algorithm.The blue dot in the MIP image bottom right marks the maximum SUV within the ROI.. The standardized uptake value (SUV) is a nuclear medicine term, used in positron emission tomography (PET) as well as in modern calibrated single photon emission tomography (SPECT) imaging for a semiquantitative analysis. [1]
Imaging is a useful tool in visualization of the radioligand after injection, with Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) being the most common types of imaging. PET scans are often utilized after radioligand administration because of the ease of use, image accuracy, and non-invasive nature.