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High white blood cell count; B-symptoms – Fever, night sweats and/or weight loss; Similar to other leukemias, B-cell prolymphocytic leukemia is often asymptomatic. The most common signs and symptoms are the result of the inability of the bone marrow to produce normal levels of blood cells: [7] Anaemia – due to lack of red blood cells
Monoclonal B-cell lymphocytosis; Other names: monoclonal lymphocytosis of undetermined significance: Specialty: Hematology, oncology: Symptoms: None: Complications: May progress to chronic lymphocytic leukemia or certain lymphoma types; increased risk of developing non-hematologic cancers, serious infections, and kidney disease
A B-cell leukemia is any of several types of lymphoid leukemia which affect B cells. [1] Types include (with ICD-O code): [citation needed] 9823/3 - B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma; 9826/3 - Acute lymphoblastic leukemia, mature B-cell type; 9833/3 - B-cell prolymphocytic leukemia; 9835/3-9836/3 - Precursor B ...
Large granular lymphocytic leukemia may involve either T-cells or NK cells; like hairy cell leukemia, which involves solely B cells, it is a rare and indolent (not aggressive) leukemia. [26] Adult T-cell leukemia is caused by human T-lymphotropic virus (HTLV), a virus similar to HIV. Like HIV, HTLV infects CD4+ T-cells and replicates within ...
The B symptoms, such as fever, night sweats, and weight loss, are often present as well. [19] Central nervous system (CNS) symptoms such as cranial neuropathies due to meningeal infiltration are identified in less than 10% of adults and less than 5% of children, particularly mature B-cell ALL (Burkitt leukemia) at presentation. [20]
In hematology, plasma cell dyscrasias (also termed plasma cell disorders and plasma cell proliferative diseases) are a spectrum of progressively more severe monoclonal gammopathies in which a clone or multiple clones of pre-malignant or malignant plasma cells (sometimes in association with lymphoplasmacytoid cells or B lymphocytes) over-produce and secrete into the blood stream a myeloma ...
The plasmablastic cells in B-cell lymphomas, including diffuse B-cell lymphomas, chronic lymphocytic leukemia/small lymphocytic lymphoma, and follicular lymphoma generally express CD20 and often express CD45 marker proteins. While PBL plasmablastic cells weakly express CD20 in 10% of cases, the strong expression of CD20 and the expression of ...
B-cell chronic lymphocytic leukemia (also known as small cell lymphocytic lymphoma) is a blood cancer that involves the B-cell lymphocytes; responsible for the creation of antibodies. Of the two general types of chronic lymphocytic leukemias (the other involving T-cells), B-cell chronic lymphocytic leukemia accounts for approximately 95 percent ...
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