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Especially, for the immune system to cause inflammatory response anywhere in the central nervous system, the cells from the immune system must pass through the blood brain barrier. In the case of myelitis, not only is the immune system dysfunctional, but the dysfunction also crosses this protective blood brain barrier to affect the spinal cord. [8]
Asian optic-spinal MS - this variant can present brain lesions like MS. [18] Longitudinally extensive myelitis or optic neuritis associated with systemic autoimmune disease. Optic neuritis or myelitis associated with lesions in specific brain areas such as the hypothalamus, periventricular nucleus, and brainstem. [19]
Transverse myelitis (TM) is a rare neurological condition wherein the spinal cord is inflamed.The adjective transverse implies that the spinal inflammation extends horizontally throughout the cross section of the spinal cord; [1] the terms partial transverse myelitis and partial myelitis are sometimes used to specify inflammation that affects only part of the width of the spinal cord. [1]
Neuroinflammation is widely regarded as chronic, as opposed to acute, inflammation of the central nervous system. [5] Acute inflammation usually follows injury to the central nervous system immediately, and is characterized by inflammatory molecules, endothelial cell activation, platelet deposition, and tissue edema. [6]
Cerebral vasculitis (sometimes the word angiitis is used instead of "vasculitis") is vasculitis (inflammation of the blood vessel wall) involving the brain and occasionally the spinal cord. [1] It affects all of the vessels: very small blood vessels ( capillaries ), medium-size blood vessels ( arterioles and venules ), or large blood vessels ...
Degenerative spinal disorders involve a loss of function in the spine. Pressure on the spinal cord and nerves may be associated with herniation or disc displacement. Brain degeneration also causes central nervous system diseases (i.e. Alzheimer's, Lewy body dementia, Parkinson's, and Huntington's diseases).
Foix–Alajouanine syndrome, also called subacute ascending necrotizing myelitis, [1] is a disease caused by an arteriovenous malformation of the spinal cord. [2] In particular, most cases involve dural arteriovenous malformations that present in the lower thoracic or lumbar spinal cord.
Sectional organization of spinal cord. The spinal cord is the main pathway for information connecting the brain and peripheral nervous system. [3] [4] Much shorter than its protecting spinal column, the human spinal cord originates in the brainstem, passes through the foramen magnum, and continues through to the conus medullaris near the second lumbar vertebra before terminating in a fibrous ...