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The glomerular filtration rate (GFR) describes the volume of fluid filtered from the renal (kidney) glomerular capillaries into the Bowman's capsule per unit time. [3] Creatinine clearance (C Cr) is the volume of blood plasma that is cleared of creatinine per unit time and is a useful measure for approximating the GFR.
Fig.1) Schematic diagram of the nephron (yellow), relevant circulation (red/blue), and the four methods of altering the filtrate. The nephron is the functional unit of the kidney. [3] This means that each separate nephron is where the main work of the kidney is performed. A nephron is made of two parts:
This diagram is a retouched picture, which means that it has been digitally altered from its original version. Modifications: translated svg file using png file. text objects are preserved as text objects for ease of future editing/translation. The original can be viewed here: Kidney nephron molar transport diagram.png: .
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The renal cortex is the outer portion of the kidney between the renal capsule and the renal medulla. [1] In the adult, it forms a continuous smooth outer zone with a number of projections (cortical columns) that extend down between the pyramids.
[2] [3] They are located on the left and right in the retroperitoneal space, and in adult humans are about 12 centimetres (4 + 1 ⁄ 2 inches) in length. [4] [5] They receive blood from the paired renal arteries; blood exits into the paired renal veins. Each kidney is attached to a ureter, a tube that carries excreted urine to the bladder.
The renal medulla (Latin: medulla renis 'marrow of the kidney') is the innermost part of the kidney. The renal medulla is split up into a number of sections, known as the renal pyramids. Blood enters into the kidney via the renal artery, which then splits up to form the segmental arteries which then branch to form interlobar arteries.
Metanephros is the most complex form of kidney. [44] Each metanephric kidney is characterized by a large number of nephrons and a highly branched system of collecting tubules and ducts, [28] that open into the ureter. [48] Such branching in the metanephros is unique in relation to the pronephros and mesonephros. [44]