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How telling people about the side effects of a drug can make them sick SEE ALSO: 11 key findings from one of the most comprehensive reports ever on the health effects of marijuana
The psychoactive effects of cannabis, known as a "high", are subjective and vary among persons and the method of use. When THC enters the blood stream and reaches the brain, it binds to cannabinoid receptors. The endogenous ligand of these receptors is anandamide, the effects of which THC emulates.
D’Souza added that cannabis use can have serious impacts on the developing brain because of its effects on the endocannabinoid system, a complex signaling system in the brain that marijuana targets.
Over time, the marijuana gateway hypothesis has been studied more and more. In one published study, the use of marijuana was shown not a reliable gateway cause of illicit drug use. [67] However, social factors and environment influence drug use and abuse, making the gateway effects of cannabis different for those in differing social circumstances.
The Centers for Disease Control and Prevention notes that marijuana can absolutely affect a person's brain health — causing changes in memory, attention, learning ability and even mood —and ...
Laboratory experiments have shown that cannabinoids found in marijuana may have analgesic and anti-inflammatory effects. [23] In 2014, the American Academy of Neurology reviewed all available findings levering the use of marijuana to treat brain diseases. The result was that the scientific evidence is weak that cannabis in any form serves as ...
The phrase entourage effect was introduced in 1999. [9] [10] While originally identified as a novel method of endocannabinoid regulation by which multiple endogenous chemical species display a cooperative effect in eliciting a cellular response, the term has evolved to describe the polypharmacy effects of combined cannabis phytochemicals or whole plant extracts. [11]
On the positive side, a 2020 ... that regular marijuana use can speed up the start of symptoms of mood disorders like bipolar disorder and major depression, along with anxiety disorders ...