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Interphase is the phase of the cell cycle in which a typical cell spends most of its life. Interphase is the "daily living" or metabolic phase of the cell, in which the cell obtains nutrients and metabolizes them, grows, replicates its DNA in preparation for mitosis , and conducts other "normal" cell functions.
The eukaryotic cell cycle consists of four distinct phases: G 1 phase, S phase (synthesis), G 2 phase (collectively known as interphase) and M phase (mitosis and cytokinesis). M phase is itself composed of two tightly coupled processes: mitosis, in which the cell's nucleus divides, and cytokinesis, in which the cell's cytoplasm and cell membrane divides forming two daughter cells.
Within the cell cycle, there is a stringent set of regulations known as the cell cycle control system that controls the timing and coordination of the phases to ensure a correct order of events. Biochemical triggers known as cyclin-dependent kinases (Cdks) switch on cell cycles events at the corrected time and in the correct order to prevent ...
Figure 1: Schematic of the cell cycle. outer ring: I = Interphase, M = Mitosis; inner ring: M = Mitosis, G 1 = Gap 1, G 2 = Gap 2, S = Synthesis; not in ring: G 0 = Gap 0/Resting. Replication timing refers to the order in which segments of DNA along the length of a chromosome are duplicated.
In human tissue culture cells, the two condensin complexes are regulated differently during the mitotic cell cycle (Figure 4). [55] [56] Condensin II is present within the cell nucleus during interphase and participates in an early stage of chromosome condensation within the prophase nucleus.
The overall structure of the chromatin network further depends on the stage of the cell cycle. During interphase, the chromatin is structurally loose to allow access to RNA and DNA polymerases that transcribe and replicate the DNA. The local structure of chromatin during interphase depends on the specific genes present in the DNA.
The interphase is a much longer phase of the cell cycle than the relatively short M phase. During interphase the cell prepares itself for the process of cell division. Interphase is divided into three subphases: G 1 (first gap), S (synthesis), and G 2 (second gap). During all three parts of interphase, the cell grows by producing proteins and ...
All living organisms are the products of repeated rounds of cell growth and division. [5] During this process, known as the cell cycle, a cell duplicates its contents and then divides in two. The purpose of the cell cycle is to accurately duplicate each organism's DNA and then divide the cell and its contents evenly between the two resulting cells.