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The United States Food and Drug Administration's Investigational New Drug (IND) program is the means by which a pharmaceutical company obtains permission to start human clinical trials and to ship an experimental drug across state lines (usually to clinical investigators) before a marketing application for the drug has been approved.
Cary–Blair transport medium is a solution used to preserve fecal clinical specimens and rectal swabs after collection. The medium was devised by Sylvia G. Cary and Eugene B. Blair in 1964, [1] who noted it allowed for longer-term recovery of Salmonella, Shigella, Vibrio, and Pasteurella than other transport media.
Variety of microbiological samples. A laboratory specimen is sometimes a biological specimen of a medical patient's tissue, fluids, or other samples used for laboratory analysis to assist in differential diagnosis or staging of a disease process. These specimens are often the most reliable method of diagnosis, depending on the ailment.
Also biobanks, which do specimen storage, cannot take full responsibility for specimen integrity, because before they take custody of samples someone must collect and process them and effects such as RNA degradation are more likely to occur from delayed sample processing than inadequate storage.
Pre-shipment inspection (also preshipment inspection or PSI) is a part of supply chain management and an important quality control method for checking the quality of goods clients buy from suppliers.
For example, different types of samples must be collected in appropriate tubes to maintain the integrity of the sample and stored at appropriate temperatures (usually 4 °C) to preserve the virus and prevent bacterial or fungal growth. Sometimes multiple sites may also be sampled. [citation needed] Types of samples include the following:
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A sample of saliva can also be collected from the mouth. Excision (cutting out), a surgical method for the removal of solid or soft tissue samples. Puncture (also called centesis ) followed by aspiration is the main method used for sampling of many types of tissues and body fluids.