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Gout is a form of inflammatory arthritis caused by uric acid crystals in the joints. Learn about the risk factors, signs, diagnosis, prevention, and treatment of gout from this comprehensive article.
The HGPRT deficiency causes a build-up of uric acid in all body fluids. The combination of increased synthesis and decreased utilization of purines leads to high levels of uric acid production. This results in both high levels of uric acid in the blood and urine, associated with severe gout and kidney problems.
Uric acid is a heterocyclic compound with the formula C5H4N4O3 and a diprotic acid with pKa1 = 5.4 and pKa2 = 10.3. It is a product of purine metabolism and a component of urine, and it forms salts called urates and acid urates.
Unless high blood levels of uric acid are determined in a clinical laboratory, hyperuricemia may not cause noticeable symptoms in most people. [5] Development of gout – which is a painful, short-term disorder – is the most common consequence of hyperuricemia, which causes deposition of uric acid crystals usually in joints of the extremities, but may also induce formation of kidney stones ...
Hypouricemia is a low level of uric acid in blood serum that may be benign or a sign of a medical condition. Learn about the causes, symptoms, diagnosis and treatment of hypouricemia, as well as the drugs, diet and genetics that affect it.
Drop Acid, which will be released on February 15, 2022, is an informative read for anyone looking to learn more about the truth about uric acid and its long-term effects on the human body. Show ...
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