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Haplogroup C-M217 is the only variety of Haplogroup C-M130 to be found among Native Americans, among whom it reaches its highest frequency in Na-Dené populations. It would also make sense that this lineage may have originated in the Americas as that is the only Variety found amongst the aboriginal population.
Haplogroup C is believed to have arisen in East Asia [4] some 24,000 years before present. It is a descendant of the haplogroup M.Haplogroup C shares six mutations downstream of the MRCA of haplogroup M with haplogroup Z and five mutations downstream of the MRCA of haplogroup M with other members of haplogroup M8.
In human genetics, a human Y-chromosome DNA haplogroup is a haplogroup defined by specific mutations in the non-recombining portions of DNA on the male-specific Y chromosome (Y-DNA). Individuals within a haplogroup share similar numbers of short tandem repeats (STRs) and single-nucleotide polymorphisms (SNPs). [ 2 ]
Y-Chromosome Haplogroups all form "family trees" or "phylogenies", with both branches or sub-clades diverging from a common haplogroup ancestor, and also with all haplogroups themselves linked into one family tree which traces back ultimately to the most recent shared male line ancestor of all men alive today, called in popular science Y ...
Haplogroup C-M217, also known as C2 (and previously as C3), [1] is a Y-chromosome DNA haplogroup.It is the most frequently occurring branch of the wider Haplogroup C (M130). ). It is found mostly in Central Asia, Eastern Siberia and significant frequencies in parts of East Asia and Southeast Asia including some populations in the Caucasus, Middle East, South Asia, East Eur
Two haplogroups are presented: Q-M242 and C-M130. [3] Haplogroup Q-M242, containing subgroups, is found in each tested population within the Americas. Haplogroup C-M130 is almost absent in Central and South America. [3] "Haplogroup C-M130 is dated to have expanded ~30,000 to 25,000 BP and haplogroup Q-M242 ~18,000 to 15,000 BP". [3]
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A haplotype is a group of alleles in an organism that are inherited together from a single parent, [1] [2] and a haplogroup (haploid from the Greek: ἁπλοῦς, haploûs, "onefold, simple" and English: group) is a group of similar haplotypes that share a common ancestor with a single-nucleotide polymorphism mutation. [3]