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  2. Spironolactone - Wikipedia

    en.wikipedia.org/wiki/Spironolactone

    It accounts for about 80% of the potassium-sparing effect of spironolactone. [11] [185] [186] Canrenone, the second major active form of spironolactone. It accounts for around 10 to 25% of the potassium-sparing effect of spironolactone. [187]

  3. Pharmacodynamics of spironolactone - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics_of...

    7α-Thiomethylspironolactone, the major active form of spironolactone. It accounts for about 80% of the potassium-sparing effect of spironolactone. [1] [2] [3] Canrenone, the second major active form of spironolactone. It accounts for around 10 to 25% of the potassium-sparing effect of spironolactone. [4

  4. Potassium-sparing diuretic - Wikipedia

    en.wikipedia.org/wiki/Potassium-sparing_diuretic

    Potassium-sparing diuretics or antikaliuretics [1] refer to drugs that cause diuresis without causing potassium loss in the urine. [2] They are typically used as an adjunct in management of hypertension , cirrhosis , and congestive heart failure . [ 3 ]

  5. Mineralocorticoid receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/Mineralocorticoid_receptor...

    However, spironolactone is metabolized to three active metabolites, which give it prolonged activity (13.8 – 16. 5 hours). Spironolactone has a long half-life and is excreted 47-51% through kidneys. Patients with chronic kidney disease therefore require close monitoring when taking the drug. Spironolactone is also eliminated through feces (35-41%

  6. Diuretic - Wikipedia

    en.wikipedia.org/wiki/Diuretic

    The thiazides and potassium-sparing diuretics are considered to be calcium-sparing diuretics. [6] The thiazides cause a net decrease in calcium lost in urine. [7] The potassium-sparing diuretics cause a net increase in calcium lost in urine, but the increase is much smaller than the increase associated with other diuretic classes. [7]

  7. The new college student sex trend and why it's so dangerous

    www.aol.com/college-student-sex-trend-why...

    The Food and Drug Administration has issued warnings about multiple honey packet brands, citing hidden drug ingredients in the product. The big problem, doctors say, is that when you ingest a ...

  8. Hyperkalemia - Wikipedia

    en.wikipedia.org/wiki/Hyperkalemia

    A number of medications can also cause high blood potassium including spironolactone, NSAIDs, and angiotensin converting enzyme inhibitors. [1] The severity is divided into mild (5.5–5.9 mmol/L), moderate (6.0–6.4 mmol/L), and severe (>6.5 mmol/L). [3] High levels can be detected on an electrocardiogram (ECG). [3]

  9. You're Probably Eating Way Too Much Salt. Here's How to Tell.

    www.aol.com/youre-probably-eating-way-too...

    NO SURPRISE HERE: Americans are eating too much salt. According to the FDA, Americans eat on average about 3,400 mg of sodium per day—more than 50 percent of the dietary guidelines ...

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