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  2. Hyperkalemia - Wikipedia

    en.wikipedia.org/wiki/Hyperkalemia

    Hyperkalemia is an elevated level of potassium (K +) in the blood. [1] Normal potassium levels are between 3.5 and 5.0 mmol/L (3.5 and 5.0 mEq/L ) with levels above 5.5 mmol/L defined as hyperkalemia.

  3. Potassium binder - Wikipedia

    en.wikipedia.org/wiki/Potassium_binder

    Potassium binders are medications that bind potassium ions in the gastrointestinal tract, thereby preventing its intestinal absorption. This category formerly consisted solely of polystyrene sulfonate, a polyanionic resin attached to a cation, administered either orally or by retention enema to patients who are at risk of developing hyperkalaemia (abnormal high serum potassium levels).

  4. Salbutamol - Wikipedia

    en.wikipedia.org/wiki/Salbutamol

    Salbutamol, also known as albuterol and sold under the brand name Ventolin among others, [1] is a medication that opens up the medium and large airways in the lungs. [8] It is a short-acting β 2 adrenergic receptor agonist that causes relaxation of airway smooth muscle . [ 8 ]

  5. Long-acting beta-adrenoceptor agonist - Wikipedia

    en.wikipedia.org/wiki/Long-acting_beta...

    LABAs are designed to reduce the need for shorter-acting β 2 agonists such as salbutamol (albuterol), as they have an approximately twelve-hour duration of action, compared to about five hours for salbutamol, making them candidates for sparing high doses of corticosteroids [citation needed] or treating nocturnal asthma and providing ...

  6. High anion gap metabolic acidosis - Wikipedia

    en.wikipedia.org/wiki/High_anion_gap_metabolic...

    High anion gap metabolic acidosis is typically caused by acid produced by the body. More rarely, it may be caused by ingesting methanol or overdosing on aspirin . [ 1 ] [ 2 ] The delta ratio is a formula that can be used to assess elevated anion gap metabolic acidosis and to evaluate whether mixed acid base disorder (metabolic acidosis) is present.

  7. Discovery and development of beta2 agonists - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    In the mid-1960s, albuterol or salbutamol was discovered, followed by tributalin and fenoterol a few years later. Albuterol and terbutaline gave fewer side effects, such as increased heart rate, than isoproterenol. The pharmaceutical company Glaxo discovered salmeterol, a long-acting β 2-agonist that had bronchodilation activity for up to 12 ...

  8. Neuromuscular-blocking drug - Wikipedia

    en.wikipedia.org/wiki/Neuromuscular-blocking_drug

    Very flexible molecules are, in fact, weak neuromuscular inhibitors with flat dose-response curves. On the other hand, stiff or rigid molecules tend to fit well or not at all. If the lowest-energy conformation fits, the compound has high potency because there is a great concentration of molecules close to the lowest-energy conformation.

  9. Nonsteroidal anti-inflammatory drug - Wikipedia

    en.wikipedia.org/wiki/Nonsteroidal_anti...

    Large doses slowly reduce the immune response as the immune cells are renewed at a much lower rate. [112] Causing a gradual reduction of the immune system, much slower and less noticeable than the immediate effect of Corticosteroids. [112] The effect significantly increases with dosage, in a nearly exponential rate. [112]