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A popular example of drug–food interaction is the effect of grapefruit on the metabolism of drugs. Interactions may occur by simultaneous targeting of receptors, directly or indirectly. For example, both Zolpidem and alcohol affect GABA A receptors, and their simultaneous consumption results in the overstimulation of the receptor, which can ...
Version 3.0 also included drug transporter data, drug pathway data, drug pricing, patent and manufacturing data as well as data on >5000 experimental drugs. Version 4.0 was released in 2014. [ 4 ] This version included 1558 FDA-approved small molecule drugs, 155 biotech drugs and 4200 unique drug targets.
The Biological General Repository for Interaction Datasets (BioGRID) is a curated biological database of protein-protein interactions, genetic interactions, chemical interactions, and post-translational modifications created in 2003 (originally referred to as simply the General Repository for Interaction Datasets (GRID) [2] by Mike Tyers, Bobby-Joe Breitkreutz, and Chris Stark at the Lunenfeld ...
Examples of alpha-glucosidase inhibitors include: Acarbose- Precose or Glucobay; Miglitol – Glyset; Voglibose; Even though the drugs have a similar mechanism of action, there are subtle differences between acarbose and miglitol. Acarbose is an oligosaccharide, whereas miglitol resembles a monosaccharide. Miglitol is fairly well absorbed by ...
No clinically relevant interactions have been found in studies with a number of drugs that are known for their interaction potential (simvastatin, warfarin, digoxin, and oral contraceptives). Nonetheless, since albiglutide slows gastric emptying, it could conceivably increase absorption of other drugs if taken at the same time.
A smaller study on metformin also found that the average weight lost in 154 patients was between 5.6 and 7 kilograms — or 13 to 15 ... Of the diabetes drugs prescribed off-label for weight ...
Arrhythmia Dataset Data for a group of patients, of which some have cardiac arrhythmia. 276 features for each instance. 452 Text Classification 1998 [272] [273] H. Altay et al. Diabetes 130-US hospitals for years 1999–2008 Dataset 9 years of readmission data across 130 US hospitals for patients with diabetes.
Adults with mild type 2 diabetes might improve their insulin sensitivity by following a low-carb diet, thus potentially eliminating the need for medication, a new study suggests.