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The standard for diagnosis of aortic stenosis is non-invasive testing with echocardiography. Cardiac catheterization is reserved for cases in which there is a discrepancy between the clinical picture and non-invasive testing, due to risks inherent to crossing the aortic valve, such as stroke. [7]
Another important cause of aortic stenosis is chronic rheumatic fever, which can cause repeated inflammation and repair, leading to fibrosis. In this case, the leaflets can actually fuse together, called commissural fusion, which can be an important distinction from the type caused by mechanical stress over time.
Mitral stenosis is almost always caused by rheumatic heart disease. [16] Less than 10% of aortic stenosis is caused by rheumatic heart disease. [15] [16] Rheumatic fever can also cause chronic mitral and aortic regurgitation. [16]
Aortic stenosis can also be caused by rheumatic fever and degenerative calcification. [7] The most common congenital heart defect is the bicuspid aortic valve (fusion of two cusps together) commonly found in Turner syndrome .
Cardiovascular disease (CVD) is any disease involving the heart or blood vessels. [3] CVDs constitute a class of diseases that includes: coronary artery diseases (e.g. angina, heart attack), heart failure, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, arrhythmia, congenital heart disease, valvular heart disease, carditis, aortic aneurysms, peripheral artery disease ...
Rheumatic fever can be prevented by effectively and promptly treating strep throat with antibiotics. [45] Globally, rheumatic fever is seen in populations that are socioeconomically disadvantaged and with limited access to health care. [46] Overcrowding [46] [47] and exposure to domestic air pollution [47] have been cited as associated risk ...
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