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Likelihood Ratio: An example "test" is that the physical exam finding of bulging flanks has a positive likelihood ratio of 2.0 for ascites. Estimated change in probability: Based on table above, a likelihood ratio of 2.0 corresponds to an approximately +15% increase in probability.
The positive predictive value (PPV), or precision, is defined as = + = where a "true positive" is the event that the test makes a positive prediction, and the subject has a positive result under the gold standard, and a "false positive" is the event that the test makes a positive prediction, and the subject has a negative result under the gold standard.
Diagram relating pre- and post-test probabilities, with the green curve (upper left half) representing a positive test, and the red curve (lower right half) representing a negative test, for the case of 90% sensitivity and 90% specificity, corresponding to a likelihood ratio positive of 9, and a likelihood ratio negative of 0.111.
The numerator of this ratio is less than the denominator; so, the likelihood ratio is between 0 and 1. Low values of the likelihood ratio mean that the observed result was much less likely to occur under the null hypothesis as compared to the alternative.
Positive likelihood ratio = sensitivity / (1 − specificity) ≈ 0.67 / (1 − 0.91) ≈ 7.4 Negative likelihood ratio = (1 − sensitivity) / specificity ≈ (1 − 0.67) / 0.91 ≈ 0.37 Prevalence threshold = P T = T P R ( − T N R + 1 ) + T N R − 1 ( T P R + T N R − 1 ) {\displaystyle PT={\frac {{\sqrt {TPR(-TNR+1)}}+TNR-1}{(TPR+TNR-1 ...
FILE - Chicago Bears offensive coordinator Shane Waldron walks the sideline during the second half of a preseason NFL football game against the Buffalo Bills in Orchard Park, N.Y., Aug. 10, 2024 ...
The likelihood ratio is central to likelihoodist statistics: the law of likelihood states that degree to which data (considered as evidence) supports one parameter value versus another is measured by the likelihood ratio. In frequentist inference, the likelihood ratio is the basis for a test statistic, the so-called likelihood-ratio test.
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