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Megestrol acetate (MGA), sold under the brand name Megace among others, is a progestin medication which is used mainly as an appetite stimulant to treat wasting syndromes such as cachexia. [ 2 ] [ 5 ] [ 7 ] [ 1 ] It is also used to treat breast cancer and endometrial cancer , and has been used in birth control .
Progestogens, such as megestrol acetate and medroxyprogesterone acetate, are effective at high doses in the treatment of advanced postmenopausal breast cancer. [ 38 ] [ 39 ] They have been extensively evaluated as a second-line therapy for this indication. [ 38 ]
[10] [4] It is used as a method of birth control and as a part of menopausal hormone therapy. [10] [4] It is also used to treat endometriosis, abnormal uterine bleeding, paraphilia, and certain types of cancer. [10] The medication is available both alone and in combination with an estrogen.
Your bleeding patterns will start to change as you event menopause, but bleeding after menopause can be the sign of a more serious medical issue.
Megestrol (INN Tooltip International Nonproprietary Name, BAN Tooltip British Approved Name) is a progestin of the 17α-hydroxyprogesterone group which was, until recently, never marketed or used clinically. [1] [2] It is now used for treatments of disease-related weight loss, endometrial cancer, and breast cancer. [3]
What does bleeding after menopause mean? Several things can cause postmenopausal bleeding, and a common one is vaginal dryness. Tang says the vagina can get easily irritated, which can lead to ...
Megestrol acetate (Megace) – 20 mg, 40 mg – approved specifically for the treatment of breast and endometrial cancer [46] and for the treatment of anorexia, cachexia, and weight loss in patients with AIDS Tooltip acquired immunodeficiency syndrome [47] Norethisterone acetate (Aygestin, Norlutate) – 5 mg
Depending on the presumed underlying cause of bleeding, medical management with progestogen-only pills, combined oral contraceptives, or tranexamic acid may be appropriate. One study found that 76% of patients who took oral medroxyprogesterone acetate (20 mg) for treatment of bleeding unrelated to pregnancy saw resolution of their bleeding. The ...
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