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  2. Vascular resistance - Wikipedia

    en.wikipedia.org/wiki/Vascular_resistance

    Vascular resistance is the resistance that must be overcome for blood to flow through the circulatory system.The resistance offered by the systemic circulation is known as the systemic vascular resistance or may sometimes be called by another term total peripheral resistance, while the resistance caused by the pulmonary circulation is known as the pulmonary vascular resistance.

  3. TPR - Wikipedia

    en.wikipedia.org/wiki/TPR

    Total peripheral resistance, vascular resistance; Translocated promoter region, part of a protein; Other uses in science and technology. True positive rate, a ...

  4. Cardiovascular physiology - Wikipedia

    en.wikipedia.org/wiki/Cardiovascular_physiology

    Total peripheral resistance (primarily due to vasoconstriction of arteries) Inotropic state; In turn, this can have a significant impact upon several other variables: Stroke volume; Cardiac output; Pressure Pulse pressure (systolic pressure - diastolic pressure) Mean arterial pressure (usually approximated with diastolic pressure + 1/3 pulse ...

  5. Hypertension - Wikipedia

    en.wikipedia.org/wiki/Hypertension

    In most people with established essential hypertension, increased resistance to blood flow (total peripheral resistance) accounts for the high pressure while cardiac output remains normal. [71] There is evidence that some younger people with prehypertension or 'borderline hypertension' have high cardiac output, an elevated heart rate and normal ...

  6. Hemodynamics - Wikipedia

    en.wikipedia.org/wiki/Hemodynamics

    The pressure drop of the arterioles is the product of flow rate and resistance: ∆P=Q xresistance. The high resistance observed in the arterioles, which factor largely in the ∆P is a result of a smaller radius of about 30 μm. [24] The smaller the radius of a tube, the larger the resistance to fluid flow.

  7. Pathophysiology of heart failure - Wikipedia

    en.wikipedia.org/wiki/Pathophysiology_of_heart...

    This helps restore blood pressure but also increases the total peripheral resistance, increasing the workload of the heart. Binding to beta-1 receptors in the myocardium increases the heart rate and makes contractions more forceful in an attempt to increase cardiac output. This also, however, increases the amount of work the heart has to perform.

  8. Handgrip maneuver - Wikipedia

    en.wikipedia.org/wiki/Handgrip_maneuver

    The handgrip maneuver increases afterload [1] by squeezing the arterioles and increasing total peripheral resistance. [2] Cardiology

  9. Myogenic mechanism - Wikipedia

    en.wikipedia.org/wiki/Myogenic_mechanism

    Increased contraction increases the total peripheral resistance (TPR) and this further increases the mean arterial pressure (MAP). This is explained by the following equation: =, where CO is the cardiac output, which is the volume of blood pumped by the heart in one minute.