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The G4 virus, also known as the "G4 swine flu virus" (G4) and "G4 EA H1N1", is a swine influenza virus strain discovered in China. [68] The virus is a variant genotype 4 (G4) Eurasian avian-like (EA) H1N1 virus that mainly affects pigs, but there is some evidence of it infecting people. [68]
The initial outbreak of a novel [2] swine-origin H1N1 flu pandemic in 2009 and the virus strain that caused it were called by many names. In July 2009, WHO experts named the virus "pandemic H1N1/09 virus" to distinguish it from both various seasonal H1N1 virus strains and the 1918 flu pandemic H1N1 strain. [citation needed]
Swine influenza virus (SIV) or swine-origin influenza virus (S-OIV) refers to any strain of the influenza family of viruses that is endemic in pigs. [2] As of 2009, identified SIV strains include influenza C and the subtypes of influenza A known as H1N1 , H1N2 , H2N1, H3N1 , H3N2 , and H2N3 .
The 2009 swine flu pandemic, caused by the H1N1/swine flu/influenza virus and declared by the World Health Organization (WHO) from June 2009 to August 2010, was the third recent flu pandemic involving the H1N1 virus (the first being the 1918–1920 Spanish flu pandemic and the second being the 1977 Russian flu).
In the 21st century, a strain of H1N1 flu (since titled "H1N1pdm09") was antigenically very different from previous H1N1 strains, leading to a pandemic in 2009. Because of its close resemblance to some strains circulating in pigs, this became known as "swine flu". [46] Influenza A virus continues to circulate and evolve in birds and pigs.
Future flu pandemics, which may be caused by an influenza virus of avian origin, [35] are viewed as almost inevitable, and increased globalization has made it easier for a pandemic virus to spread, [34] so there are continual efforts to prepare for future pandemics [76] and improve the prevention and treatment of influenza. [1]
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