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The cost must also take into account personnel costs, data processing costs, legal, communications and other costs. One way to assess this is via commercial offerings. The first such whole diploid genome sequencing (6 billion bp, 3 billion from each parent) was from Knome and their price dropped from $350,000 in 2008 to $99,000 in 2009.
Rothberg estimated the cost of the sequence—the first personal genome produced using a next-generation sequencing platform—at $1 million. [12] Watson's genome sequence was published in 2008. [13] A number of scientists have highlighted the cost of additional analysis after performing sequencing.
Veritas Genetics is a personal genomics startup based in Danvers, Massachusetts. [1] According to the company's press release, it was among the first companies to offer whole genome sequencing and interpretation for under $1,000. [2] It was co-founded in 2014 by George M. Church, Mirza Cifric, Preston Estep, and Jonathan Zhao. [3]
Science loves a great story. Archimedes leaping from the bath, shouting "eureka!" The apple that dropped on Isaac Newton's head. Alexander Fleming's accidental discovery of penicillin in a petri dish.
Since the Human Genome Project first sequenced the human genome from 1987 to 2004 at a cost of US$3 billion, costs have fallen precipitously, outpacing even Moore's law, and were ≈US$1,000 in 2015. More widely available genome sequencing has led to more data on variants of uncertain significance.
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In June 2009, Illumina announced that they were launching their own Personal Full Genome Sequencing Service at a depth of 30× for $48,000 per genome. [60] [61] In August, the founder of Helicos Biosciences, Stephen Quake, stated that using the company's Single Molecule Sequencer he sequenced his own full genome for less than $50,000. [62]
However, in 2023 no specific statement of sequencing location exists in the FAQs. Nebula Genomics said that this partnership is made to bring down the cost of whole-genome sequencing since normally it has a cost that makes it inaccessible to most people. [15]
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