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An advisory committee to the FDA agreed this week that oral decongestant medications with phenylephrine are ineffective. ... If a cold or viral upper respiratory infection lasts seven to 10 days ...
After an FDA advisory committee said the decongestant phenylephrine, an ingredient found in many oral cold and flu medications, is ineffective, experts weigh in on alternatives.
A decongestant, or nasal decongestant, is a type of pharmaceutical drug that is used to relieve nasal congestion in the upper respiratory tract. The active ingredient in most decongestants is either pseudoephedrine or phenylephrine (the latter of which has disputed effectiveness ).
Nasal obstruction characterized by insufficient airflow through the nose can be a subjective sensation or the result of objective pathology. [10] It is difficult to quantify by subjective complaints or clinical examinations alone, hence both clinicians and researchers depend both on concurrent subjective assessment and on objective measurement of the nasal airway.
There are different therapeutic approaches for acute rhinosinusitis. Among other things, pain killers, decongestant nose drops or sprays to reduce the local swelling of the mucosa, topical steroids and phytotherapeutics can be used. In case of a bacterial rhinosinusitis, antibiotics are a typical therapeutic treatment. [4]
The decongestant effect is due to constriction of large veins in the nose which swell up during the inflammation of any infection or allergy of the nose. The smaller arteries are also constricted and this causes the colour of the nasal epithelium to be visibly paler after dosage.
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