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This is an accepted version of this page This is the latest accepted revision, reviewed on 23 January 2025. DNA molecule containing genetic material of a cell This article is about the DNA molecule. For the genetic algorithm, see Chromosome (genetic algorithm). Chromosome (10 7 - 10 10 bp) DNA Gene (10 3 - 10 6 bp) Function A chromosome and its packaged long strand of DNA unraveled. The DNA's ...
A major difference between the two genomes is human chromosome 2, which is equivalent to a fusion product of chimpanzee chromosomes 12 and 13. [110] (later renamed to chromosomes 2A and 2B, respectively).
The human genome has a total length of approximately 3.2 billion base pairs (bp) in 46 chromosomes of DNA as well as slightly under 17,000 bp DNA in cellular mitochondria. In 2015, the typical difference between an individual's genome and the reference genome was estimated at 20 million base pairs (or 0.6% of the total). [2]
Most organisms have the same genomic DNA in every cell; however, only certain genes are active in each cell to allow for cell function and differentiation within the body. [2] gDNA predominantly resides in the cell nucleus packed into dense chromosome structures. Chromatin refers to the combination of DNA and proteins that make up chromosomes.
Eukaryotic genomes are composed of one or more linear DNA chromosomes. The number of chromosomes varies widely from Jack jumper ants and an asexual nemotode, [28] which each have only one pair, to a fern species that has 720 pairs. [29] It is surprising the amount of DNA that eukaryotic genomes contain compared to other genomes.
Associated enhancers may be many kilobase away, or even on entirely different chromosomes operating via physical contact between two chromosomes. [69] [70] A single gene can encode multiple different functional products by alternative splicing, and conversely a gene may be split across chromosomes but those transcripts are concatenated back ...
A chromosome in a diploid organism is hemizygous when only one copy is present. [2] The cell or organism is called a hemizygote. Hemizygosity is also observed when one copy of a gene is deleted, or, in the heterogametic sex, when a gene is located on a sex chromosome.
A chromosome now consists of genes as data objects of the gene types, whereby, depending on the application, each gene type occurs exactly once as a gene or can be contained in the chromosome any number of times. The latter leads to chromosomes of dynamic length, as they are required for some problems.