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Avapritinib, sold under the brand name Ayvakit among others, is a medication used for the treatment of advanced systemic mastocytosis and indolent systemic mastocytosis. It is also used for the treatment of tumors due to one specific rare mutation: it is specifically intended for adults with unresectable or metastatic gastrointestinal stromal tumor (GIST) that harbor a platelet-derived growth ...
Drug resistance, such as antimicrobial resistance or antineoplastic resistance, may make the first-line drug ineffective, especially in case of multidrug-resistant pathogens and tumors. Such an alternative may be outside of extant regulatory requirements or medical best practices, in which case it may be viewed as salvage therapy .
Stomach cancer, also known as gastric cancer, is a malignant tumor of the stomach. It's a cancer that develops from the lining of the stomach. [10] Most cases of stomach cancers are gastric carcinomas, which can be divided into a number of subtypes, including gastric adenocarcinomas. [2]
[citation needed] Additionally, in the absence of specific therapy, the diagnostic categorization had only a limited influence on prognosis and therapy. The understanding of GIST biology changed significantly with identification of the molecular basis of GIST, [2]: 1065 particularly c-KIT. Historically, literature reviews prior to the molecular ...
Cancer treatment has progressed to combine different methods to improve the chances of survival. Surgery and radiation therapy are used to control cancer in specific areas, while systemic therapies (such as chemotherapy , endocrine therapy , targeted therapies , and bisphosphonates ) are used to manage widespread cancer or cancer that has ...
The chemotherapy drug 5-FU can be toxic to some people with cancer. A quick, cheap test can show if chemo is safe for a patient, but few doctors order it. A quick, cheap test could protect against ...
FOLFOX is given directly into the bloodstream through an intravenous line. It can be given through a thin, short tube (a cannula) put into a vein in the arm each time one has a treatment. It may also be given through a central line, a portacath, or a PICC line. These are long, plastic tubes that give the drugs directly into a large vein in the ...
Related: Heart Announces Additional 2025 North American Tour Dates Following Ann Wilson's Cancer Diagnosis The rocker announced in July that she’d recently undergone surgery for cancer, and as a ...