Search results
Results from the WOW.Com Content Network
Cross-bridge theory states that actin and myosin form a protein complex (classically called actomyosin) by attachment of myosin head on the actin filament, thereby forming a sort of cross-bridge between the two filaments. The sliding filament theory is a widely accepted explanation of the mechanism that underlies muscle contraction.
Cross-bridge cycle. Cross-bridge cycling is a sequence of molecular events that underlies the sliding filament theory. A cross-bridge is a myosin projection, consisting of two myosin heads, that extends from the thick filaments. [1] Each myosin head has two binding sites: one for adenosine triphosphate (ATP) and another for actin.
The binding of the myosin head to actin is known as a cross-bridge. A molecule, called adenosine triphosphate (ATP) which is produced by an intracellular structure called a mitochondrion, is then used, as a source of energy, to help move the myosin head, carrying the actin. As a result, the actin slides across the myosin filament shortening the ...
Deputy Editor Tara Seplavy and Senior Photographer Trevor Raab explain how cyclocross workouts can help you improve strength, power, and bike handling skills.
Activation consists of phosphorylation of a serine on position 19 (Ser19) on the MLC 20 light chain, which causes a conformational change that increases the angle in the neck domain of the myosin heavy chain, [8] which corresponds to the part of the cross-bridge cycle where the myosin head is unattached to the actin filament and relocates to ...
Get AOL Mail for FREE! Manage your email like never before with travel, photo & document views. Personalize your inbox with themes & tabs. You've Got Mail!
Calmodulin plays an important role in excitation contraction (EC) coupling and the initiation of the cross-bridge cycling in smooth muscle, ultimately causing smooth muscle contraction. [34] In order to activate contraction of smooth muscle, the head of the myosin light chain must be phosphorylated.
Upgrade to a faster, more secure version of a supported browser. It's free and it only takes a few moments: