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Prepubertal hypertrichosis is characterized by an excess of hair growth, seen during birth and progressing during childhood. [3] [6] In generalized hypertrichosis, excessive hair growth occurs all over the body, whereas in localized hypertrichosis, excessive hair growth only occurs in certain areas of the body. [2]
Hirsutism is a type of hypertrichosis exclusive to women and children, resulting from an excess of androgen-sensitive hair growth. [16] Patients with hirsutism exhibit patterns of adult male hair growth. [1] Chest and back hair are often present on women with hirsutism. [16] Hirsutism is both congenital and acquired.
Hair diseases are illnesses that impact the persistence and regular growth of hair. Types of hair diseases include folliculitis , hirsutism , hypertrichosis , hypotrichosis ( alopecia ), Menkes kinky hair syndrome , monilethrix , and piedra .
Barber-Say syndrome (BSS) is a very rare congenital disorder associated with excessive hair growth (hypertrichosis), fragile skin, eyelid deformities , and an overly broad mouth (macrostomia). [ 1 ] Barber-Say syndrome is phenotypically similar to Ablepharon macrostomia syndrome , which is also associated with dominant mutations in TWIST2 .
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. [3] [4] Cancer can be difficult to diagnose because its signs and symptoms are often nonspecific, meaning they may be general phenomena that do not point directly to a specific disease process. [5]
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Latitudinal and longitudinal growth may be affected. [1] [2] [3] Nevertheless, the musculoskeletal features are central to the diagnosis of some syndromes such as Proteus syndrome. [2] The time of presentation of children with overgrowth syndromes is an important contributor to the differential diagnosis.
Limited growth, full-body alopecia (hair loss), and a distinctive appearance (a small face with a shallow, recessed jaw and a pinched nose) are all characteristics of progeria. [5] Signs and symptoms of this progressive disease tend to become more marked as the child ages.
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