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Schizophrenia is thought to have a heritable component in some people, but many people who appear to carry schizophrenia-associated genes may not develop the disease. [13] Research has shown that schizophrenia is a polygenic disorder and that genetic vulnerability to schizophrenia is highly multifactorial , caused by the interactions of several ...
The causes of schizophrenia that underlie the development of schizophrenia, a psychiatric disorder, are complex and not clearly understood.A number of hypotheses including the dopamine hypothesis, and the glutamate hypothesis have been put forward in an attempt to explain the link between altered brain function and the symptoms and development of schizophrenia.
A possible link between the urban environment and pollution has been suggested to be the cause of the elevated risk of schizophrenia. [113] Other risk factors include social isolation , immigration related to social adversity and racial discrimination, family dysfunction, unemployment, and poor housing conditions.
'This will turn out to be the most important break in the disease,' the Broad Institute's director Eric Lander said.
Furthermore, people with a history of cannabis use develop psychotic symptoms earlier than those who have never used cannabis. [67] Some debate exists regarding the causal relationship between cannabis use and psychosis with some studies suggesting that cannabis use hastens the onset of psychosis primarily in those with pre-existing vulnerability.
Schizophrenia affects around 0.3–0.7% of the general population at some point in life (i.e. lifetime prevalence), [1] or 21 million people worldwide as of 2020 (about one of every 285). [2] By using precise methods in its diagnosis and a large, representative population, schizophrenia seems to occur with relative consistency over time during ...
Eccentric behavior and discomfort with relationships define the disorder, and people may develop schizophrenia later.
During most of the 20th century, mental illness was ascribable to problematic relationships between children and their parents. This view was held well into the late 1990s, in which people still believed this child-parent relationship was a large determinant of severe mental illness, such as depression and schizophrenia.
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