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Metronidazole, sold under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication. [10] It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. [10]
Metronidazole is an antibiotic with an off-label use in eradicating H. pylori for treating gastric ulceration. Resistance of metronidazole is above 15% worldwide. [ 32 ] It is likely to be resistant so is not the first line choice of treatment. [ 44 ]
Suppose it has a long lifetime in the body, and only ten percent of it is cleared from the blood each day by the liver and kidneys. Suppose also that the drug works best when the total amount in the body is exactly one gram. So, the maintenance dose of foosporin is 100 milligrams (100 mg) per day—just enough to offset the amount cleared.
2nd week: PPI (standard dose), amoxicillin 1 g, metronidazole 0.5 g and clarithromycin 0.5 g bid First line therapy Bismuth-containing quadruple therapy 10–14 PPI (standard dose) bid, tetracycline 0.5 g qid, metronidazole 0.25 g qid and bismuth standard dose qid First line or second line therapy Levofloxacin-based triple therapy 10
The antibacterial properties of bismuth were not known until much later. [1] 1875 G. Bottcher and M. Letulle hypothesize that ulcers are caused by bacteria. [1] 1880 J. Cohnheim suggests that ulcers may be caused by chemical factors. [1] 1881 Klebs notes the presence of bacteria-like organisms in the lumen of the gastric glands. [4] 1889
To reduce your risk of drug interactions, make sure to inform your healthcare provider about any medications you currently use or have recently used before taking Wellbutrin. When stopped abruptly ...
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Antimicrobial spectrum is similar to that of metronidazole and is more well tolerated; [1]: 1368 however there are concerns of lower relative efficacy. [3] It was first introduced for treating trichomoniasis before being recognized for its broad anti-protozoan and anti-anaerobic-bacterial capacities.