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"Advances in inhaler therapy for asthma and chronic obstructive pulmonary disease: a comprehensive review of Fostair and Trimbow". Journal of Pharmacy and Pharmacology . doi : 10.1093/jpp/rgae090 .
Formoterol is marketed in three forms: a dry-powder inhaler (DPI), a metered-dose inhaler (MDI) and an inhalation solution, under various brand names including Atock, Atimos/Atimos Modulite, Foradil/Foradile, Fostair, Oxeze/Oxis, Perforomist and Symbicort. Foradil/Foradile capsules for oral inhalation (Schering-Plough in the U.S., Novartis rest ...
MDI canister and actuator components from H&T Presspart. A metered-dose inhaler consists of three major components: the canister, which is produced in aluminum or stainless steel by means of deep drawing, where the formulation resides; the metering valve, which allows a metered quantity of the formulation to be dispensed with each actuation; and an actuator (or mouthpiece) which enables the ...
Triamcinolone acetonide, sold under the brand name Kenalog among others, is a synthetic corticosteroid medication used topically to treat various skin conditions, [13] to relieve the discomfort of mouth sores, and by injection into joints to treat various joint conditions.
[5] [6] It is used to treat rhinorrhea (runny nose) caused by allergic rhinitis, nonallergic rhinitis, [5] and the common cold. [7] [2] It is used by metered-dose manual pump spray. Onset of action is within an hour. [7] Common side effects of inhalant use include dry mouth, cough, inflammation of the airways, [3] and shortness of breath. [8]
Trimbow is indicated for the maintenance treatment in adults with moderate to severe chronic obstructive pulmonary disease (COPD) and asthma who are not adequately treated by a combination of an inhaled corticosteroid and a long-acting beta2-agonist or a combination of a long-acting beta2-agonist and a long-acting muscarinic antagonist.
It contains budesonide, a steroid; and formoterol, a long-acting β 2-agonist (LABA). [2] The product monograph does not support its use for sudden worsening or treatment of active bronchospasm. [2] However, a 2020 review of the literature does support such use. [6] It is used by breathing in the medication. [2]
StAR has thus far been found in all tissues that can produce steroids, including the adrenal cortex, the gonads, the brain and the nonhuman placenta. [10] One known exception is the human placenta. Substances that suppress StAR activity, like those listed below, can cause endocrine disrupting effects, including altered steroid hormone levels ...