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MDCalc was founded by two emergency physicians, Graham Walker, MD, and Joseph Habboushe, MD, MBA, [5] and provides over 500 medical calculators and other clinical decision-support tools. [6] The MDCalc.com website was launched in 2005. [5] In 2016, MDCalc launched an iOS app, [7] followed by an Android app in 2017. [8]
Gentamicin is a type of aminoglycoside [5] and works by disrupting the ability of the bacteria to make proteins, which typically kills the bacteria. [5] Gentamicin is naturally produced by the bacterium Micromonospora purpurea, [9] [5] was patented in 1962, approved for medical use in 1964. [10]
Medical calculators arose because modern medicine makes frequent use of scores and indices that put physicians' memory and calculation skills to the test. [2] The advent of personal computers, the Internet and Web, and more recently personal digital assistants (PDAs) have formed an environment conducive to their development, spread and use.
Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside .
Aminoglycoside-3'-phosphotransferase (APH(3')), also known as aminoglycoside kinase, is an enzyme that primarily catalyzes the addition of phosphate from ATP to the 3'-hydroxyl group of a 4,6-disubstituted aminoglycoside, such as kanamycin. [2]
Pages in category "Aminoglycoside antibiotics" The following 34 pages are in this category, out of 34 total. This list may not reflect recent changes. ...
In enzymology, an aminoglycoside N3'-acetyltransferase (EC 2.3.1.81) is an enzyme that catalyzes the chemical reaction acetyl-CoA + a 2-deoxystreptamine antibiotic ⇌ {\displaystyle \rightleftharpoons } CoA + N 3 '-acetyl-2-deoxystreptamine antibiotic
An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]