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The RAIU test is a reliable measurement when using a dedicated probe with a reproducibility of 1 percent and a 95%-least-significant-change of 3 percent. [3] The normal uptake is between 15 and 25 percent, but this may be forced down if, in the meantime, the patient has eaten foods high in iodine, such as dairy products and seafood. [4]
Radioactive iodine (iodine-131) alone can potentially worsen thyrotoxicosis in the first few days after treatment. One side effect of treatment is an initial period of a few days of increased hyperthyroid symptoms. This occurs because when the radioactive iodine destroys the thyroid cells, they can release thyroid hormone into the blood stream.
The uptake test involves administering a dose of radioactive iodine (radioiodine), traditionally iodine-131 (131 I), and more recently iodine-123 (123 I). Iodine-123 may be the preferred radionuclide in some clinics due to its more favorable radiation dosimetry (i.e. less radiation dose to the person per unit administered radioactivity) and a ...
Hypothyroidism is common in pregnancy with an estimated prevalence of 2-3% and 0.3-0.5% for subclinical and overt hypothyroidism respectively. [8] Endemic iodine deficiency accounts for most hypothyroidism in pregnant women worldwide while chronic autoimmune thyroiditis is the most common cause of hypothyroidism in iodine sufficient parts of the world.
Molar pregnancy: Trauma (i.e. hip fracture) Burns Myocardial infarction: Pulmonary embolism: Stroke: Heart failure: Radioactive iodine treatment Medication side effect (anesthetics, salicylate, pseudoephedrine, amiodarone) Exposure to iodinated contrast: Withdrawal of antithyroid treatment Emotional stress Intense exercise
The test was first introduced in 1956, using iodine-131 diodrast. [25] [26] Later developments included iodine-131, and then iodine-123, labelled ortho-Iodohippuric acid (OIH, marketed as Hippuran). [27] [28] 99m Tc-MAG3 has replaced 131 I-OIH because of better quality imaging regardless of the level of kidney function, [29] and lower radiation ...
Around the world, the most common cause of congenital hypothyroidism is iodine deficiency, but in most of the developed world and areas of adequate environmental iodine, cases are due to a combination of known and unknown causes. Most commonly there is a defect of development of the thyroid gland itself, resulting in an absent (athyreosis) or ...
Complications: During pregnancy can result in cretinism in the baby [5] Usual onset > 60 years old [3] Causes: Iodine deficiency, Hashimoto's thyroiditis [3] Diagnostic method: Blood tests (thyroid-stimulating hormone, thyroxine) [3] Differential diagnosis: Depression, dementia, heart failure, chronic fatigue syndrome [6] Prevention: Salt ...