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Average number of moderate-to-severe hot flashes per week with placebo and different doses of oral estradiol in menopausal women [40] [41]. Estradiol is used in menopausal hormone therapy to prevent and treat moderate to severe menopausal symptoms such as hot flashes, vaginal dryness and atrophy, and osteoporosis (bone loss). [11]
A single administration of 4 mg micronized estradiol (two 2-mg Estrace tablets) under the tongue, considered a very high dose of sublingual estradiol, has been found to result in maximal levels of estradiol of 1759 ± 704 pg/mL, with a range of 634 to 2840 pg/mL, after 1 hour in a mixed group of normotensive and hypertensive postmenopausal ...
Levonorgestrel is a hormonal medication which is used in a number of birth control methods. [3] [7] It is combined with an estrogen to make combination birth control pills. [8]As an emergency birth control, sold under the brand names Plan B One-Step and Julie, among others, it is useful within 72 hours of unprotected sex.
Hormone replacement therapy consisting of systemic treatment with estrogen alone or in combination with a progestogen, has well-documented and considerable beneficial effects on the skin of postmenopausal women. [25] [26] These benefits include increased skin collagen content, skin thickness and elasticity, and skin hydration and surface lipids.
While identifying the causes of tongue thrust, it is important to remember that the resting posture of the tongue, jaw, and lips are crucial to the normal development of the mouth and its structures. If the tongue rests against the upper front teeth, the teeth may protrude forward, and adverse tongue pressure can restrict the development of the ...
Tongue diseases can be congenital or acquired, and are multiple in number. Considered according to a surgical sieve , some example conditions which can involve the tongue are discussed below. Glossitis is a general term for tongue inflammation , which can have various etiologies , e.g. infection .
Aphthous stomatitis is one of the most common diseases of the oral mucosa, and is thought to affect about 20% of the general population to some degree. [4] The symptoms range from a minor nuisance to being disabling in their impact on eating, swallowing, and talking, and the severe forms can cause people to lose weight.
[3] [7] No related signs of disease are found in the mouth. [3] People with burning mouth syndrome may also have a subjective xerostomia (dry mouth sensation where no cause can be found such as reduced salivary flow), paraesthesia (altered sensation such as tingling in the mouth), or an altered sense of taste or smell. [3]