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  2. Chronic obstructive pulmonary disease - Wikipedia

    en.wikipedia.org/wiki/Chronic_obstructive...

    Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by chronic respiratory symptoms and airflow limitation. [8] GOLD 2024 defined COPD as a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea or shortness of breath, cough, sputum production or exacerbations) due to abnormalities of the airways (bronchitis ...

  3. Health effects of tobacco - Wikipedia

    en.wikipedia.org/wiki/Health_effects_of_tobacco

    The association of smoking with lung cancer and COPD are among strongest, both in the public perception and etiologically. Among male smokers, the lifetime risk of developing lung cancer is 17.2%; among female smokers, the risk is 11.6%. This risk is significantly lower in nonsmokers: 1.3% in men and 1.4% in women. [26]

  4. Obstructive lung disease - Wikipedia

    en.wikipedia.org/wiki/Obstructive_lung_disease

    COPD is generally irreversible although lung function can partially recover if the patient stops smoking. Smoking cessation is an essential aspect of treatment. [9] Pulmonary rehabilitation programmes involve intensive exercise training combined with education and are effective in improving shortness of breath.

  5. Smoker's macrophages - Wikipedia

    en.wikipedia.org/wiki/Smoker's_macrophages

    Smoking-related deaths in firsthand and secondhand smokers in the US between 2005 and 2009 (no data available for secondhand smokers with COPD deaths [7]) The morbidity of cigarette smoking is nearly 50% with 7 million first-hand smokers and 1.2 millions second hand smokers killed each year. [8]

  6. Smoking cessation - Wikipedia

    en.wikipedia.org/wiki/Smoking_cessation

    Tobacco use leads most commonly to diseases affecting the heart and lungs, with smoking being a major risk factor for heart attacks, [5] [6] strokes, [7] chronic obstructive pulmonary disease (COPD), [8] idiopathic pulmonary fibrosis (IPF), [9] emphysema, [8] and various types and subtypes of cancers [10] (particularly lung cancer, cancers of ...

  7. Epigenetic effects of smoking - Wikipedia

    en.wikipedia.org/wiki/Epigenetic_effects_of_smoking

    Though smoking leads to an overall decrease in DNA methylation, several critical genes become hypermethylated. Two of the most noteworthy of these genes are p16 and p53. These genes are critical to cell cycle regulation and were shown to have higher levels of methylation in smokers than in non smokers. [3]

  8. Emphysema - Wikipedia

    en.wikipedia.org/wiki/Emphysema

    When associated with significant airflow limitation, emphysema is a major subtype of chronic obstructive pulmonary disease (COPD), a progressive lung disease characterized by long-term breathing problems and poor airflow. [10] [11] Without COPD, the finding of emphysema on a CT lung scan still confers a higher mortality risk in tobacco smokers ...

  9. Tobacco harm reduction - Wikipedia

    en.wikipedia.org/wiki/Tobacco_harm_reduction

    None of the three main causes of death from smoking—lung cancer, chronic obstructive pulmonary disease (COPD) (including emphysema and chronic bronchitis), and cardiovascular diseases—is caused primarily by nicotine; the main reason smoking is deadly is the toxic mix of chemicals in smoke produced by the combustion of tobacco. Products that ...

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