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Pentamidine is an antimicrobial medication used to treat African trypanosomiasis, leishmaniasis, Balamuthia infections, [2] babesiosis, and to prevent and treat pneumocystis pneumonia (PCP) in people with poor immune function. [1]
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Phenyltropanes (PTs) are a family of chemical compounds originally derived from structural modification of cocaine.The main feature differentiating phenyltropanes from cocaine is that they lack the ester functionality at the 3-position terminating in the benzene; and thusly the phenyl is attached direct to the tropane skeleton with no further spacer (therefore the name "phenyl"-tropane) that ...
3-Methyl-2-pentanone (methyl sec-butyl ketone) is an aliphatic ketone and isomer of 2-hexanone. [2] References This page was last edited on 17 November 2024, at 23: ...
The determination of chemical structure include (mainly): for the gaseous state: gas electron diffraction [ 2 ] and microwave spectroscopy [ 3 ] for the liquid state: NMR spectroscopy [ 4 ] (note, obtaining precise structural information from liquids and solutions is still rather difficult compared to gases and crystalline solids)
The sensory function of substance P is thought to be related to the transmission of pain information into the central nervous system. Substance P coexists with the excitatory neurotransmitter glutamate in primary afferents that respond to painful stimulation. [ 30 ]
Furthermore, the preceding sequence Gln-Gly-Gln-Cys is conserved in both isozymes for both human and horse, which is consistent with Cys-302 being crucial to catalytic function. [2] As discovered by site-directed mutagenesis, glutamate-268 is a key component of liver acetaldehyde dehydrogenase and is also critical to catalytic activity. Since ...
AP-2 complex. The AP2 adaptor complex is a multimeric protein that works on the cell membrane to internalize cargo in clathrin-mediated endocytosis. [1] It is a stable complex of four adaptins which give rise to a structure that has a core domain and two appendage domains attached to the core domain by polypeptide linkers.