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Chondrocalcinosis or cartilage calcification is calcification (accumulation of calcium salts) in hyaline cartilage and/or fibrocartilage. [1] Chondrocalcinosis is an observation that can be visualized through diagnostic imaging tests such as X-rays , CT , MRI , and ultrasound .
X-ray of a knee with chondrocalcinosis. Medical imaging, consisting of x-ray, CT, MRI, or ultrasound may detect chondrocalcinosis within the affected joint, indicating a substantial amount of calcium crystal deposition within the cartilage or ligaments. [2] Ultrasound is a reliable method to diagnose CPPD. [8]
The prognosis for children with JIA has improved dramatically over recent decades, particularly with the introduction of biological therapies and a shift towards more aggressive treatment strategies. JIA treatment aims for normal physical and psychosocial functioning, which is an achievable goal for some children with this condition.
In pseudogout/chondrocalcinosis/calcium pyrophosphate deposition disease, the crystal is calcium pyrophosphate. Diabetic arthropathy (M14.2, E10-E14) is caused by diabetes. Neuropathic arthropathy (M14.6) is associated with a loss of sensation. Spondylarthropathy is any form of arthropathy of the vertebral column. [5]
In one study, 81% of children with active systemic symptoms had abnormal echocardiographic findings, and 36% of patients had an effusion or pericardial thickening. The majority of pericardial effusions don't cause any symptoms; they can only be identified by echocardiography and don't show any overt cardiomegaly or usual ECG abnormalities.
Deposition of crystals in joints; Calcium pyrophosphate dihydrate crystal formation: . Increased production of inorganic pyrophosphate; Decreased levels of pyrophosphatase in cartilage
Most of the other disorders diagnosed in infancy, childhood, or adolescence involve anxiety. If the child is continually put in anxiety producing situations, they could show symptoms of these disorders. Usually, the symptoms will be mild and the child will not get help, which may cause the symptoms to become worse. [22]
Generally speaking, symptoms typically include redness, heat and pain in a single joint associated with a decreased ability to move the joint. Onset is usually rapid. Other symptoms may include fever, weakness and headache. Occasionally, more than one joint may be involved, especially in neonates, younger children and immunocompromised individuals.